Results 61 to 70 of about 1,156 (145)
Research progress in the relationship between iron deficiency and tic disorder [PDF]
Tic disorder is a common neurodevelopmental disorder disease in children， with a high prevalence and different clinical manifestations among individuals.
Wang Yun, Xiang Jingjing, Zheng Qian, Bai Jinxiu
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Zhongguo shiyan zhenduanxue, 2014 NAFLD是遗传环境代谢应激相关性疾病[1-4]。近年来,人们发现在NAFLD的发病机制中,铁作为一种独立危险因素起着重要的作用。铁超负荷除了通过诱发氧应激造成过氧化损伤,还与胰岛素抵抗有着密切的关系。脂联素[5,6]作为一种改善胰岛素抵抗的保护性因子在NAFLD的发生发展中起着重要作用,有研究报道[7,8],脂联素可通过减少脂质合成,增加脂肪酸氧化,减少肝脏脂质含量。本研究,
李琪, 王晓峰
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Construction of Co-Delivered Curcumin and EGCG Liposomes and Their Effects on Neuroinflammation(共递送姜黄素和EGCG脂质体的构建及其对神经炎症的作用) [PDF]
Shipin kexue jishu xuebaoTo overcome the limitations of two bioactive components, curcumin and epigallocatechin gallate (EGCG), in terms of stability and metabolic kinetics, and to further exploit their synergistic antioxidant and anti-inflammatory effects, liposomes co ...
MA Dexue(马德雪) +3 more
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Effect of Interactions Between Grass Carp Spoilage Bacteria Pseudomonas putida and Shewanella putrefaciens on TheirSpoilage Potentials(草鱼腐败菌Pseudomonas putida和Shewanella putrefaciens互作对其致腐能力的影响) [PDF]
Shipin kexue jishu xuebaoGrass carp are perishable due to the growth of microorganisms during storage, which restricts the development of its processing industry to some extent. Microbial interactions are important factors affecting food spoilage.
ZHUANG Shuai(庄帅) +3 more
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浙江大学学报. 医学版目的借助生物信息学技术探究骨质疏松中铁死亡的基因靶点并利用体外实验验证骨质疏松中铁死亡关键基因，探讨铁死亡在骨质疏松中的作用机制。方法在基因芯片公共数据库中筛选骨质疏松相关基因数据集GSE35958并进行数据矫正分析；在FerrDb数据库中筛选铁死亡相关基因，并与数据集GSE35958差异表达基因取交集得到骨质疏松中铁死亡相关差异表达基因，然后进行差异表达基因的基因本体（GO）与京都基因和基因组数据库（KEGG）富集分析；分析差异表达基因的Spearman相关系数，并绘制蛋白质-蛋白质相互作用网络 ...
夏 玉双 +6 more
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Zhongguo shiyan zhenduanxue, 2016 目的探讨缺铁性贫血对不同基因型α地中海贫血筛查的影响,评估HbA2与红细胞各指标在鉴别缺铁性贫血和各种基因型α地中海贫血中的作用。方法严格筛选正常人群样本、α地中海贫血患者样本、缺铁性贫血患者样本和α地中海贫血合并缺铁性贫血患者样本,进行血红蛋白电泳、血常规、铁蛋白和地中海贫血基因诊断,统计分析不同检测指标在各样本组差异。结果缺铁性贫血的HbA2平均水平低于α地中海贫血,HbH病患者HbA2水平低于缺铁性贫血。鉴别正常人群和单纯α地中海贫血时,MCH比MCV有更高的敏感性。鉴别α地中海贫血和缺铁性贫血时,
陈卫东, 周宇, 王秋
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Protective effect of dihydromyricetin against hippocampal neuronal injury caused by iron overload and its mechanism [PDF]
Objective To investigate the protective effect of dihydromyricetin (DMY) against injury of primary hip-pocampal neurons caused by ferric ammonium citrate (FAC) and its mechanism.
SUI Yunjie, MA Zegang
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Zhongshan Daxue xuebao. Yixue kexue ban铁与高血压的关系近年来已成为心血管领域的重要前沿方向。铁死亡（ferroptosis）作为近年发现的一种铁依赖性细胞死亡形式，已被证实在多数心血管疾病及其相关疾病的发生发展中扮演着十分重要的角色。铁死亡的核心机制涉及铁代谢紊乱、脂质过氧化反应以及抗氧化系统的损伤，这些机制在高血压的病理进程中起着重要作用。铁死亡中铁代谢失衡和脂质过氧化这两者是导致高血压疾病相关血管损伤、血管重构以及高血压靶器官损害的关键因素。本文系统梳理了铁死亡与高血压之间的分子关联及其病理生理机制网络，重点探讨了铁死亡中铁代谢紊乱 ...
刘琪悦, 刘丽军
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野生动物学报, 2008 目的:通过对9只来自野外和园内养大的云豹毛中锌、铜、铁、钙4种元素检测,了解云豹对这4种元素代谢特点与产生脱毛症的关系。方法:从云豹尾部的上1/3处采毛,用原子吸收光谱法检测。结果:在所检测的9只云豹中,其中3只患脱毛症的云豹毛中铜元素含量都低于4.4μg/g,其他3种元素所测结果表明与脱毛症均没有直接关系。结论:铜元素缺乏可能与云豹患脱毛症关系密切。
马再玉 +3 more
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