骨髓单个核细胞抗人球蛋白分型试验在免疫相关性全血细胞减少症（IRP）中的诊断意义
Zhongguo shiyan zhenduanxue, 2009 本文研究骨髓单个核细胞抗人球蛋白分型试验在诊断免疫相关性全血细胞减少症（IRP）的临床意义。90例血细胞减少症患者入院后完善血清铁蛋白（SF）,叶酸（FA）及维生素B12浓度,免疫学检查,血小板抗体,乙肝六项,甲肝及丙肝抗体、溶血相关检查、骨髓涂片及染色体核型分析等常规检查。实验组:28例拟诊免疫相关性全血细胞减少症。阳性对照组:自身免疫性溶血性贫血19例。阴性对照组:43例,包括再生障碍性贫血12例、骨髓增生异常综合征14例、巨幼细胞性贫血10例,阵发性睡眠型血红蛋白尿3例,缺铁性贫血4例 ...
李燕 +4 more
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Zhongguo shiyan zhenduanxue, 2015 目的研究广东地区不同类型地中海贫血(地贫)患儿血清可溶性转铁蛋白受体(sTfR)水平与患儿临床表现的关系。方法对14例静止型α地贫,47例标准型α地贫,27例血红蛋白H(HbH)病,14例异常血红蛋白Constant Spring(HbCS)复合HbH病,59例β地贫杂合子,31例β地贫纯合子或双重杂合子和50例正常健康儿童的血红蛋白(Hb)含量,血清铁(SI)水平及sTfR水平进行检测,并对结果进行统计学分析。结果静止型α地贫患儿的sTfR水平与正常对照相比无显著性差异 ...
张力, 高秀蓉, 颜慕霞, 李彦媚
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[Evaluation of the short-term prognosis of patients with HBV-related acute-on-chronic liver failure by combining ferritin with COSSH-ACLF II score]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLiu YX +5 more
europepmc +1 more source
EGCG调控AMPK/GSK-3β/Nrf2抑制铁死亡减轻阿霉素诱导的心脏毒性
Zhongguo shiyan zhenduanxue目的探究表没食子儿茶素没食子酸酯（EGCG）是否通过AMPK/GSK-3β/Nrf2信号通路抑制铁死亡，从而减轻阿霉素心脏毒性。方法建立阿霉素心肌损伤模型，将C57BL/6J小鼠随机分为3组：Control组、DOX组、DOX+EGCG组。HE染色观察心肌形态学变化，试剂盒检测心肌组织丙二醛（MDA）和铁离子（Fe2+）含量。免疫荧光检测活性氧（ROS）水平。Western blot检测AMPK、GSK3β、Nrf2蛋白表达。建立H9C2心肌细胞阿霉素损伤模型。实验分为5组：Control组、DOX组 ...
韩必成 +3 more
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[Bioinformatics screening and analysis of key genes of ferroptosis and autophagy in alcoholic liver disease and their validation]. [PDF]
Zhonghua Gan Zang Bing Za ZhiZhang QQ +4 more
europepmc +1 more source
[Research progress on lactylation modification in pathogenesis of osteoarthritis]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiWu Y +7 more
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[Research Advances on the Autophagy and Ferroptosis in the Development and Treatment of Lung Cancer]. [PDF]
Zhongguo Fei Ai Za ZhiJiang C +6 more
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[Role and mechanism of ubiquitin-specific protease 35 in ferroptosis of rheumatoid arthritis-fibroblast like synoviocytes]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanFeng L, Hong L, Chen Y, Cai X.
europepmc +1 more source
[Dehydrated hereditary stomatocytosis in 23 cases: a single-center retrospective cohort study from Peking Union Medical College Hospital (2018-2024)]. [PDF]
Zhonghua Xue Ye Xue Za ZhiWang Q +5 more
europepmc +1 more source
[Role and Mechanism of High Mobility Group Box 1 in Mediating Depression-Like Behaviors in Mice via Regulation of the 5-Hydroxytryptamine Receptor 7 Signaling Pathway]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanDU O, Duan S, Tang L, DU J.
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