骨髓干细胞移植治疗对肝豆状核变性早期TX小鼠脑肾铜代谢的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 探讨骨髓干细胞移植对于疾病早期肝豆状核变性模型鼠———TX小鼠脑、肾组织铜代谢的影响。【方法】4~5周龄的雄性DL小鼠50只为供体;2月龄的TX小鼠50只为受体(雌∶雄=3:2),随机分为移植组和对照组各25只(雌∶雄=3:2)。分离供体小鼠骨髓干细胞并标记CM-DiI荧光,经尾静脉注入移植组TX小鼠体内,每只小鼠0.2 mL(1.2 × 107个细胞),对照组动物注入等量平衡盐液体。移植后的1、2、4、8、12周处死动物检测脑、肾铜含量情况,并以CM-DiI荧光示踪技术考察干细胞在受体鼠脑 ...
doaj
[Role and mechanism of copper overload-mediated endoplasmic reticulum stress in vascular endothelial injury in Kawasaki disease]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiWen SF +4 more
europepmc +1 more source
Role of copper and its complexes in cardiovascular diseases. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Zhu W, Zhang Y, Luo X, Peng J.
europepmc +1 more source
[LncRNA Meg3 expression level is negatively correlated with liver fibrosis severity in patients with Wilson disease]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHua D +8 more
europepmc +1 more source
Drug-assisted synthesis of copper nanoparticles and their induction of cuproptosis and necrosis for breast cancer therapy. [PDF]
J Zhejiang Univ Sci BWang Y +5 more
europepmc +1 more source
[Risk factors for ventilator-associated pneumonia in patients with chest trauma in intensive care unit]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanZhao J +6 more
europepmc +1 more source
[Analysis of nutritional status before and after different induction therapies in children with Crohn's disease]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiChen LL, Yu Y, Luo YY, Chen J.
europepmc +1 more source
Research progress in cuproptosis in liver cancer. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Chen L, Liu D, Tan Y.
europepmc +1 more source
[Wilson's disease misdiagnosed as autoimmune hepatitis: a case report and literature review]. [PDF]
Zhonghua Gan Zang Bing Za ZhiChen LF +5 more
europepmc +1 more source