Results 11 to 20 of about 5,994 (191)
Is metformin a possible treatment for diabetic neuropathy? 二甲双胍治疗糖尿病周围神经病变——有益还是有害?
Highlights Metformin has been shown to alleviate diabetic peripheral neuropathy. The neuroprotective and analgesic effects of metformin are related to the activation of AMPK, the clearance of MGO, and the reduction of insulin resistance and neuroinflamation. AMPK activation is critical for the analgesic effect of metformin.
Juechun Wei +4 more
wiley +1 more source
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
wiley +1 more source
Botanical, Traditional Use, Phytochemical, and Toxicological of Arisaematis rhizoma
Aim of the Study. This paper summarizes the traditional uses, botany, chemical composition, pharmacology, pharmacodynamics, and toxicology of Arisaematis rhizoma (hereafter referred to as AR). In addition, the future development and research prospect of AR were discussed in detail.
Chun-yan Qi +7 more
wiley +1 more source
Traditional Chinese medicine (TCM) still needs more scientific rationale to be proven for it to be accepted further in the West. We are now in the position to propose computational hypotheses for the mode‐of‐actions (MOAs) of 45 TCM therapeutic action (sub)classes from in silico target prediction algorithms, whose target was later annotated with Kyoto ...
Siti Zuraidah Mohamad Zobir +7 more
wiley +1 more source
Genus Tinospora: Ethnopharmacology, Phytochemistry, and Pharmacology
The genus Tinospora includes 34 species, in which several herbs were used as traditional medicines by indigenous groups throughout the tropical and subtropical parts of Asia, Africa, and Australia. The extensive literature survey revealed Tinospora species to be a group of important medicinal plants used for the ethnomedical treatment of colds ...
Sensen Chi +6 more
wiley +1 more source
目的分析研究拉玛泽减痛法联合硬膜外镇痛在分娩镇痛中的临床应用效果。方法选取2019年1月—2020年1月在文昌市人民医院产科的足月产妇305例,根据随机数字表法分为观察组101例、对照组101例(拉玛泽减痛)及试验组103例(硬膜外镇痛+拉玛泽减痛)。其中观察组接受硬膜外镇痛,对照组接受拉玛泽减痛法,试验组接受拉玛泽减痛联合硬膜外镇痛。记录并比较3组孕妇的镇痛效果、分娩方式、催产素使用量、产中出血量、改良Bromage评分、产程、给药后不良反应以及新生儿Apgar评分。结果自然分娩率试验组为94.17%,
梁丹, 林苗, 林丽
doaj
Study on the Photocatalytic Degradation of Acetaminophen by TiO2/Zeolite compounds [PDF]
对乙酰氨基酚(Acetaminophen,Ace)是最常用的非抗炎解热镇痛药的主要成分,具有潜在的生态毒性,目前尚未找到一种理想而有效的处理方法。研究采用光催化氧化法对其进行光催化降解实验。TiO2以其化学稳定性、无毒性、价格低廉、光催化活性高等优异性能被广泛研究。但因其颗粒过小,易团聚,不易与水分离而受到限制。 研究以具有大表面、高吸附性能的沸石为载体,采用溶胶-凝胶法制备TiO2/沸石复合光催化材料,并借助紫外-可见漫反射(UV-VIS)、X射线衍射(XRD)、扫描电镜(SEM)、傅里叶-红外光谱 ...
王佳婕
core
A Systematic Review on Different Treatment Methods of Bone Metastasis from Cancers [PDF]
Background and objective Skeletal metastase is one of the most common complications related to advanced cancer. The aim of this study is to analyze the effectiveness and safety of radiotherapy plus intravenous bisphosphonates versus radiotherapy alone ...
Jinhui TIAN +4 more
core
摘要: (免费在线浏览)摘要:[目的]探讨双氯芬酸钠栓与硬膜外镇痛泵在剖宫产术后的镇痛效果。[方法]抽取2004年8月―2007年4月剖宫产产妇184 例,随机分为观察组和对照组,各92 例,术后分别给予双氯芬酸钠栓与硬膜外镇痛泵镇痛,观察两组镇痛效果。[结果]剖宫产术后使用双氯芬酸钠栓镇痛效果与硬膜外镇痛泵镇痛效果相当。[结论]双氯芬酸钠栓镇痛操作简便、安全、吸收快、无副反应、经济,产妇容易接受。
林秀玲, 罗琳虹
doaj
The metabolism of endogenous lipids in hepatocellular carcinoma [PDF]
研究背景:原发性肝细胞癌(以下简称原发性肝癌)是肝脏主要的恶性肿瘤,由于其起病隐匿,进展迅速,确诊时大多数患者已达到晚期或发生远处转移,治疗困难,因此提高原发性肝癌的诊断及愈后至关重要。有研究证明内源性大麻素系统可以通过多条通路产生抗肿瘤作用,但其与原发性肝癌发生发展的关系及治疗作用尚未完全阐明。 目的:本课题通过相关实验技术研究内源性大麻素系统与原发性肝癌之间的内在联系,探讨相关机制,以期发现原发性肝癌发生早期的生物标志物;并通过调控内源性脂质,探讨有效治疗原发性肝癌的特异性靶标。 方法 ...
李蕾
core

