Results 71 to 80 of about 198 (106)

[Role of gut microbiota in perioperative neurocognitive disorders after cardiopulmonary bypass surgery in rats with humanized gut flora]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Fan J, Sun Y, Liang B, Zhang X, Xiao C, Huang Z.   +5 more
europepmc   +1 more source

小胶质细胞对阿尔兹海默病发生发展的影响作用

, 2018
阿尔兹海默病（老年性痴呆,AD）是由β淀粉样蛋白（Aβ）和微管相关蛋白（Tau）聚集形成的具有毒性作用的寡聚物而引起的老年人主要以记忆力下降和脑部形成老年斑、神经纤维缠绕为特征的神经退行性疾病.小胶质细胞作为中枢神经系统中的固有免疫细胞,是脑内免疫监视的关键成分,发挥内源性免疫防御作用.正常生理状态的小胶质细胞能有效吞噬和清除毒性Aβ寡聚体,阻止AD发生.在AD病理过程中,过度激活的小胶质细胞通过补体依赖途径过度吞噬突触,导致突触丧失,同时大量释放炎症因子,促进Tau相关病理变化,对神经元造成直接损伤 ...
于晓琳, 刘小歌, 张伦
core  

[Quercetin mitigates HIV-1 gp120-induced rat astrocyte neurotoxicity <i>via</i> promoting G3BP1 disassembly in stress granules]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Huang P, Chen J, Zou J, Gao X, Cao H.
europepmc   +1 more source

[Therapeutic potential of NADH: in neurodegenerative diseases characterizde by mitochondrial dysfunction]. [PDF]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Chen Z, Wang H, Wang Q.
europepmc   +1 more source

[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Shang L, Jiang W, Zhang J, Wu W.
europepmc   +1 more source

[MiRNA-103-3p promotes neural cell autophagy by activating Wnt/β-catenin signaling via targeting rab10 in a rat model of depression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang Y, Zhang Y, Shen X, Wang G, Zhu L.
europepmc   +1 more source

[Sulforaphane reverses Aβ fiber-mediated M1 type microglia polarization and neuroinflammation-mediated necroptosis of neural stem cells by downregulating the MAPK/NF-κB signaling pathways]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Zhang J, Yang C, Zhang S, Cao T, Peng R, Guo W, Yan Y, Xie S, Peng X, Lü T, Huang T.   +10 more
europepmc   +1 more source

[The developments and applications of functional ultrasound imaging]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2022
Huang L, He Q, Wang R, Wei X, Xie G, Luo J.   +5 more
europepmc   +1 more source

Risk Factors of Caregiver Burden in Patients With Cognitive Dysfunction: A Scoping Review. [PDF]

Brain Behav
Jinheng L, Jingyi Z, Shaomei C, Danjuan Y, Liansheng W, Lixia C.   +5 more
europepmc   +1 more source

[Analysis of the global competitive landscape in artificial intelligence medical device research]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Chen J, Pan L, Long J, Yang N, Liu F, Lu Y, Ouyang Z.   +6 more
europepmc   +1 more source