Research Progress and Application of the Homeodomain-interacting Protein Kinase -2 [PDF]
Baolan LI, Wentao YUE, Wenyun JIA
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【目的】 研究血清GPBB浓度是否可以成为蒽环类药物的心脏毒性早期诊断指标。【方法】 新西兰雄性兔44只,随机分为对照组(8只)和实验组(36只)。对照组新西兰兔注射等体积的生理盐水;实验组新西兰兔每次静脉注射阿霉素2 mg/kg,每周1次,根据实验周数不同,实验组分为4组,分别为1周组(8只)、2周组(8只)、4周组(9只)和8周组(11只)。经胸超声心动图测量左室射血分数(LVEF)和左室短轴缩短分数(FS)以及E峰和A峰比率。血清GPBB浓度测量采用ELISA方法 ...
doaj
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Cai BB, Chen FF, Luo F.
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