【目的】 评估血管紧张素Ⅱ受体阻断剂(ARB)在老年糖尿病患者中应用的有效性和安全性?【方法】 56例大于65岁老年2型糖尿病患者,随机分为治疗组和对照组,治疗组予氯沙坦口服,剂量50 ~ 100 mg/d,对照组不给上述治疗?饮食?运动?降糖?降脂等治疗方法两组相同?观察患者预先设定的研究终点事件的发生率(研究终点包括血清肌酐浓度的加倍,发生终末期肾脏疾病以及死亡)和不良事件发生情况?【结果】 经过1年的观察,氯沙坦治疗组能有效地降低试验的主要研究终点发生的危险性?不良事件(如血肌肝的升高和高钾血症 ...
doaj
[Gastrodin inhibits ferroptosis to alleviate hypoxic-ischemic brain damage in neonatal mice by activating GPX4/SLC7A11/FTH1 signaling]. [PDF]
Guo T +8 more
europepmc +1 more source
[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]
Xu J +8 more
europepmc +1 more source
[<i>Danzhi Jiangtang</i> Capsule improves renal vascular endothelial function in rats with diabetic nephropathy by downregulating the Notch1/NICD/MAML1 signaling pathway]. [PDF]
Zhu S +7 more
europepmc +1 more source
[<i>Poria cocos</i> polysaccharide alleviates cyclophosphamide-induced intestinal barrier dysfunction and inflammation in mice by modulating gut flora]. [PDF]
Zhang Y +10 more
europepmc +1 more source
XuanHuGPT: parameter-efficient fine-tuning of large language model in the field of traditional Chinese medicine. [PDF]
Tong X +9 more
europepmc +1 more source
[Disrupting atherosclerotic plaque formation <i>via</i> the "<i>qi</i> meridian-blood channel": mechanism of <i>Jiangzhi Huaban</i> Decoction for regulating hepatic reverse cholesterol transport to improve atherosclerosis]. [PDF]
Wang H +8 more
europepmc +1 more source
[Molecular Mechanism of Neutrophils Driving the Progression of Lung Adenocarcinoma]. [PDF]
Li X, Li L.
europepmc +1 more source
[Efficacy of Transfer Energy Capacitive and Resistive Therapy Combined With β-Hydroxy-β-Methylbutyrate Nutritional Supplementation in Older Adults With Sarcopenic Obesity]. [PDF]
Wang R +4 more
europepmc +1 more source
[Research progress on lactylation modification in pathogenesis of osteoarthritis]. [PDF]
Wu Y +7 more
europepmc +1 more source

