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Recent Progress in Genetic Variants Associated with Cancer and their Implications in Diagnostics Development [PDF]
William CS CHO
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[Reflections on the clinical diagnosis and management of Turner syndrome]. [PDF]
Gu W, Zhao X.
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[Establishment of a canine model of vascularized allogeneic spinal cord transplantation and preliminary study on spinal cord continuity reconstruction]. [PDF]
Chen J +6 more
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[2024 American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guideline: Management of Osteoarthritis of the Hip (summary) interpretation]. [PDF]
Zhu X, Zeng Y.
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Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2011
越来越多的证据表明,雌激素对多种肿瘤的发生发展有促进作用,不仅包括雌激素靶器官肿瘤,还包括非靶器官肿瘤。雌激素通过两种不同的雌激素受体(estrogen receptor, ER)亚型——ERα和ERβ来发挥其调节作用,介导细胞增殖和分化。近几十年来,随着ERα介导的信号通路在乳腺癌中作用的阐明,针对ER信号的靶向治疗已经成功地应用于临床,其经典药物他莫昔芬是一种选择性雌激素受体调节剂(selective estrogen receptor modulator, SERM ...
Li-qiang Xu +4 more
semanticscholar +1 more source
越来越多的证据表明,雌激素对多种肿瘤的发生发展有促进作用,不仅包括雌激素靶器官肿瘤,还包括非靶器官肿瘤。雌激素通过两种不同的雌激素受体(estrogen receptor, ER)亚型——ERα和ERβ来发挥其调节作用,介导细胞增殖和分化。近几十年来,随着ERα介导的信号通路在乳腺癌中作用的阐明,针对ER信号的靶向治疗已经成功地应用于临床,其经典药物他莫昔芬是一种选择性雌激素受体调节剂(selective estrogen receptor modulator, SERM ...
Li-qiang Xu +4 more
semanticscholar +1 more source

