Results 21 to 30 of about 4,596 (150)
Expressions of Cyr61 and WISP-3 in Non-small Cell Lung Cancer and Its Clinical Significance [PDF]
Background and objective Cysteine-rich protein 61 (Cyr61) plays a role as a tumor suppressor in non-small cell lung cancer (NSCLC). Cyr61 and WISP-3 have a very significant sequence homology, belonging to the same CCN gene family.
Chunwei ZHANG +3 more
core
目的检测氯通道ClC-2在人非小细胞肺癌中的表达情况,探讨ClC-2在非小细胞肺癌中表达的临床意义,为ClC-2成为临床肺癌治疗的新基因靶点提供新思路。方法实验分为对照组和肺良性病组、肺鳞癌组和肺腺癌组,应用半定量RT-PCR及Western blot方法检测各组ClC-2mRNA及ClC-2蛋白表达水平并对ClC-2在非小细胞肺癌中的表达情况进行初步分析。结果 ClC-2mRNA表达水平上与对照组相比,肺鳞癌组和肺腺癌组中的ClC-2mRNA表达量明显增多,但肺良性病与正常肺组织之间无显著差异 ...
许哲男 +4 more
doaj
Clinical Observation of Erlotinib in the Treatment of Advanced Non-small Cell Lung Cancer: A Report of 92 Eases [PDF]
Background and objective Erlotinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, has been approved effective in local advanced or metastatic non-small cell lung cancer (NSCLC).
Aiqin GU +5 more
core
人类软骨糖蛋白-39在非小细胞肺癌患者血清中的含量与临床意义研究
目的检测人类软骨糖蛋白-39(YKL-40)在非小细胞肺癌患者血清中的含量,并探讨其在肺癌临床诊断中的意义。方法采集我院收治的非小细胞肺癌患者(40例)和正常人(40例)血液,所有患者均经过痰脱落细胞检测,支气管检查等最终获得病理学证据,确诊为非小细胞肺癌。采用酶联免疫吸附法(ELISA)检测收集样本中YKL-40的浓度,并分析实验结果。结果非小细胞癌患者血液中YKL-40含量比正常人高 ...
苏春霞, 王凌, 孟秀清, 韩果花
doaj
肺多性癌(Pulmonary pleomorphic carcinoma PC)是指鳞状细胞癌、腺癌或大细胞癌中含有梭形细胞和/或巨细胞成分(梭形细胞或巨细胞成分至少占整个肿瘤的10%),或仅含有梭形细胞和巨细胞成分的癌,是一类分化较差的非小细胞肺癌[1]。肺多形性癌极少见 ...
陈常娣, 于金燕, 王娇, 尹金植
doaj
The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
core
DNA倍体联合LunX mRNA检测在非小细胞肺癌胸水中的诊断价值
目的探讨胸水LunX mRNA表达及DNA异倍体分析对非小细胞肺癌患者的临床指导意义。方法收集46例非小细胞肺癌患者胸水,22例非肺癌肿瘤胸水和15例肺部良性疾病胸水作为对照。采用荧光定量RT-PCR技术检测LunX mRNA表达情况,流式细胞技术检测胸水脱落细胞DNA倍体变化。结果良恶性胸水DI、增殖指数有显著差别((P0.05)。LunX mRNA阳性表达率在非小细胞肺癌组中为91.3%(42/46),显著高于其他两对照组 ...
马寅芙 +4 more
doaj
A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
core
TACE with Ar-He Cryosurgery Combined Minimal Invasive Technique for the Treatment of Primary NSCLC in 139 Cases [PDF]
Background and objective TACE, Ar-He target cryosurgery and radioactive seeds implantation are the mainly micro-invasive methods in the treatment of lung cancer.
Dongmei LI +5 more
core
微小RNA-204在非小细胞肺癌中的表达及对H252癌细胞增殖及凋亡的影响
目的分析微小RNA-204在非小细胞肺癌中的表达及对H252癌细胞增殖及凋亡的影响。方法收集72例非小细胞患者癌组织与癌旁组织标本,采用实时荧光定量聚合酶链反应(qRT-PCR)检测miR-204相对表达水平;采用miR-204模拟物与抑制物转染人非小细胞肺癌H252细胞株,检测H252细胞增殖及凋亡情况。结果肺癌组织miR-204的mRNA相对表达水平明显低于癌旁组织 ...
王启船 +5 more
doaj

