BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer [PDF]
Background and objective The aim of this study is to determine the short-term efficacy, toxicity and the rate of life-quality improvement of BSD2000 deep hyperthermia combined with chemotherapy of PT regimen in patients with non-small cell lung cancer ...
Jun ZHAO, Mengxiang YANG, Yanwen WANG
core
目前,在世界范围内,肺癌已居恶性肿瘤死亡率之首,每年死于肺癌的患者超过100万人[1],其中非小细胞肺癌约占80%。尽管含铂的双药化疗在肺癌中的地位已经确立,但非小细胞肺癌的预后仍差强人意,化疗已达到其疗效平台。以EGFR基因突变为靶点的非小细胞肺癌(NSCLC)的治疗标志着肺癌的治疗已进入了个体化的时代[2-4],为NSCLC的治疗开创了一个全新的局面。大约20 ...
杨杨, 干惠珠, 卢振霞
doaj
A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
core
小细胞肺癌(Small Cell Lung Cancer,SCLC)因具有较短的倍增时间、较高的生长分数以及较早出现血行转移等特征而区别于非小细胞肺癌。虽然小细胞肺癌对化、放疗均较敏感,但绝大多数病人最终死于肿瘤复发或转移[1]。同步化放疗是局限期小细胞肺癌的标准治疗方案 ...
王伟力 +5 more
doaj
DNA Methylation and Non-small Cell Lung Cancer [PDF]
Genomic DNA methylation is a major form of epigenetic modification. Hypermethylation could affect the binding of transcription factors to DNA and change the structure of chromatin resulting in silence of tumor suppressor genes, which plays an important ...
Longbang CHEN, Youwei ZHANG
core
目的探讨组织多肽特异性抗原(TPS)在非小细胞肺癌患者血清中的表达水平及其临床应用价值。方法采用酶联免疫吸附法测定48例非小细胞肺癌患者、30例肺部良性疾病患者和40例健康受检者的血清TPS浓度水平。结果非小细胞肺癌患者血清TPS水平明显高于肺部良性疾病患者和正常对照组(P0.05)。临床分期为Ⅲ-Ⅳ期的患者的TPS浓度明显高于Ⅰ-Ⅱ期病人,差异有统计学意义 ...
魏民
doaj
Diagnostic Value of Transbronchial Needle Aspiration and Endobronchial Ultrasoundguided Transbronchial Needle Aspiration for Hilar and Mediastinal Lymph Nodes in Lung Cancer Patients [PDF]
Background and objective Transbronchial needle aspiration (TBNA) and endobronchial ultrasoundguided TBNA (EBUS-TBNA) have been applied to the diagnosis for mediastinal lymph nodes.
Hongli YI +4 more
core
目的 联合检测胸腔积液中的CYFRA2 1 -1、NSE ,研究CYFRA2 1 -1、NSE作为肿瘤标记物对肺癌诊断以及病期判断的诊断价值。方法 用全自动免疫酶标仪测定80胸腔积液中CYFRA2 1- 1、NSE的含量,其中肺癌4 9例,其他肿瘤31例。结果 非小细胞肺癌患者血清中CYFRA2 1 -1含量显著高于其他肿瘤组及小细胞肺癌组(P
宋鉴清 +5 more
doaj
Long-term Survival of Personalized Surgical Treatment of Locally Advanced Non-small Cell Lung Cancer Based on Molecular Staging [PDF]
Background and objective Approximately 35%-40% of patients with newly diagnosed non-small cell Lung cancer have locally advanced disease. The average survival time of these patients only have 6-8 months with chemotherapy.
Bin LIU +16 more
core
The Clinical Signifcance of Expression of ERCC1 and PKCalpha in Non-small Cell Lung Cancer [PDF]
Background and objective Excision repair cross-complementing 1 (Excision-Repair Cross-Complementing 1, ERCC1), an important member of the DNA repair gene family, plays a key role in nucleotide excision repair and apoptosis of tumor cells.
Guangming LI +6 more
core +1 more source

