Clinical Observation of Erlotinib in the Treatment of Advanced Non-small Cell Lung Cancer: A Report of 92 Eases [PDF]
, 2009 Background and objective Erlotinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, has been approved effective in local advanced or metastatic non-small cell lung cancer (NSCLC).
Aiqin GU +5 more
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DNA倍体联合LunX mRNA检测在非小细胞肺癌胸水中的诊断价值
Zhongguo shiyan zhenduanxue, 2013 目的探讨胸水LunX mRNA表达及DNA异倍体分析对非小细胞肺癌患者的临床指导意义。方法收集46例非小细胞肺癌患者胸水,22例非肺癌肿瘤胸水和15例肺部良性疾病胸水作为对照。采用荧光定量RT-PCR技术检测LunX mRNA表达情况,流式细胞技术检测胸水脱落细胞DNA倍体变化。结果良恶性胸水DI、增殖指数有显著差别(（P0.05）。LunX mRNA阳性表达率在非小细胞肺癌组中为91.3%（42/46）,显著高于其他两对照组 ...
马寅芙 +4 more
doaj
A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
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TACE with Ar-He Cryosurgery Combined Minimal Invasive Technique for the Treatment of Primary NSCLC in 139 Cases [PDF]
, 2010 Background and objective TACE, Ar-He target cryosurgery and radioactive seeds implantation are the mainly micro-invasive methods in the treatment of lung cancer.
Dongmei LI +5 more
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微小RNA-204在非小细胞肺癌中的表达及对H252癌细胞增殖及凋亡的影响
Zhongguo shiyan zhenduanxue, 2018 目的分析微小RNA-204在非小细胞肺癌中的表达及对H252癌细胞增殖及凋亡的影响。方法收集72例非小细胞患者癌组织与癌旁组织标本,采用实时荧光定量聚合酶链反应(qRT-PCR)检测miR-204相对表达水平;采用miR-204模拟物与抑制物转染人非小细胞肺癌H252细胞株,检测H252细胞增殖及凋亡情况。结果肺癌组织miR-204的mRNA相对表达水平明显低于癌旁组织 ...
王启船 +5 more
doaj
BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective The aim of this study is to determine the short-term efficacy, toxicity and the rate of life-quality improvement of BSD2000 deep hyperthermia combined with chemotherapy of PT regimen in patients with non-small cell lung cancer ...
Jun ZHAO, Mengxiang YANG, Yanwen WANG
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Zhongguo shiyan zhenduanxue, 2013 目前,在世界范围内,肺癌已居恶性肿瘤死亡率之首,每年死于肺癌的患者超过100万人[1],其中非小细胞肺癌约占80%。尽管含铂的双药化疗在肺癌中的地位已经确立,但非小细胞肺癌的预后仍差强人意,化疗已达到其疗效平台。以EGFR基因突变为靶点的非小细胞肺癌（NSCLC）的治疗标志着肺癌的治疗已进入了个体化的时代[2-4],为NSCLC的治疗开创了一个全新的局面。大约20 ...
杨杨, 干惠珠, 卢振霞
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A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
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Zhongguo shiyan zhenduanxue, 2013 小细胞肺癌（Small Cell Lung Cancer,SCLC）因具有较短的倍增时间、较高的生长分数以及较早出现血行转移等特征而区别于非小细胞肺癌。虽然小细胞肺癌对化、放疗均较敏感,但绝大多数病人最终死于肿瘤复发或转移[1]。同步化放疗是局限期小细胞肺癌的标准治疗方案 ...
王伟力 +5 more
doaj
DNA Methylation and Non-small Cell Lung Cancer [PDF]
, 2010 Genomic DNA methylation is a major form of epigenetic modification. Hypermethylation could affect the binding of transcription factors to DNA and change the structure of chromatin resulting in silence of tumor suppressor genes, which plays an important ...
Longbang CHEN, Youwei ZHANG
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