Results 51 to 60 of about 10,488 (236)

组织多肽特异性抗原检测在非小细胞肺癌中的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨组织多肽特异性抗原(TPS)在非小细胞肺癌患者血清中的表达水平及其临床应用价值。方法采用酶联免疫吸附法测定48例非小细胞肺癌患者、30例肺部良性疾病患者和40例健康受检者的血清TPS浓度水平。结果非小细胞肺癌患者血清TPS水平明显高于肺部良性疾病患者和正常对照组(P0.05)。临床分期为Ⅲ-Ⅳ期的患者的TPS浓度明显高于Ⅰ-Ⅱ期病人,差异有统计学意义 ...
魏民
doaj  

Diagnostic Value of Transbronchial Needle Aspiration and Endobronchial Ultrasoundguided Transbronchial Needle Aspiration for Hilar and Mediastinal Lymph Nodes in Lung Cancer Patients [PDF]

open access: yes, 2010
Background and objective Transbronchial needle aspiration (TBNA) and endobronchial ultrasoundguided TBNA (EBUS-TBNA) have been applied to the diagnosis for mediastinal lymph nodes.
Hongli YI   +4 more
core  

胸腔积液CYFRA21-1、NSE检测在肺癌诊断中的应用

open access: yesZhongguo shiyan zhenduanxue, 2005
目的 联合检测胸腔积液中的CYFRA2 1 -1、NSE ,研究CYFRA2 1 -1、NSE作为肿瘤标记物对肺癌诊断以及病期判断的诊断价值。方法 用全自动免疫酶标仪测定80胸腔积液中CYFRA2 1- 1、NSE的含量,其中肺癌4 9例,其他肿瘤31例。结果 非小细胞肺癌患者血清中CYFRA2 1 -1含量显著高于其他肿瘤组及小细胞肺癌组(P
宋鉴清   +5 more
doaj  

Long-term Survival of Personalized Surgical Treatment of Locally Advanced Non-small Cell Lung Cancer Based on Molecular Staging [PDF]

open access: yes, 2011
Background and objective Approximately 35%-40% of patients with newly diagnosed non-small cell Lung cancer have locally advanced disease. The average survival time of these patients only have 6-8 months with chemotherapy.
Bin LIU   +16 more
core  

The Clinical Signifcance of Expression of ERCC1 and PKCalpha in Non-small Cell Lung Cancer [PDF]

open access: yes, 2010
Background and objective Excision repair cross-complementing 1 (Excision-Repair Cross-Complementing 1, ERCC1), an important member of the DNA repair gene family, plays a key role in nucleotide excision repair and apoptosis of tumor cells.
Guangming LI   +6 more
core   +1 more source

蛋白质磷酸化酶抑制剂对肺癌细胞株的增殖抑制作用

open access: yesZhongguo shiyan zhenduanxue, 1998
目的探讨蛋白质磷酸化酶抑制剂对肺癌细胞株的增殖抑制作用。方法用蛋白质磷酸化酶抑制剂对6株小细胞肺癌和7株非小细胞肺癌细胞株的增殖抑制效果进行了检测,并采用免疫法,测定了蛋白质磷酸化酶抑制剂对肺癌细胞内Rb蛋白表达的影响。结果随其浓度的增加,对肺癌细胞株的增殖抑制作用增强,小细胞肺癌的半数抑制量平均值ST为95nM,UCN-01为588nM,非小细胞肺癌则分别为188nM和1029nM,ST和UCN-01可抑制肺癌细胞Rb蛋白的磷酸化。结论蛋白质磷酸化酶抑制剂通过抑制Rb蛋白的磷酸化 ...
doaj  

mTOR、LC3蛋白表达与Ⅰ期非小细胞肺癌相关性的研究

open access: yesZhongguo shiyan zhenduanxue, 2018
目的检测mTOR和LC3在Ⅰ期非小细胞肺癌组织中的表达量,探究二者与患者长期生存率的关系。方法将组织标本分为Ⅰ期非小细胞肺癌组和癌旁组织对照组,分别应用免疫组化法检测检测mTOR和LC3在两组组织中的表达量,分析比较5年存活率与mTOR和LC3蛋白表达量的关系。结果肺癌组中mTOR蛋白表达量显著高于癌旁组织对照组,差异具有统计学意义(=23.94 ...
李宇
doaj  

Detection of MTAP Protein and Gene Expression in Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective The abnormal expression of MTAP, a tumor suppressor gene, is found in a variety of tumor tissues. The aim of this study is to detect the expression of MTAP mRNA protein and the clinical significance for the therapy of non-small ...
Baoqing DING   +3 more
core  

Survival Analysis of 1,742 Patients with Stage IV Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective At present non-small cell lung cancer (NSCLC) is still the leading cause of death induced by cancer. The aim of this study is to investigate the prognostic factors of advanced NSCLC.
Baohui HAN, Hong PENG, Meili MA
core  

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