Results 61 to 70 of about 4,596 (150)
Expression and Clinical Significance of mTOR and PTEN in Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective It has been proved that mTOR was an important signal transduction molecular and protein kinase regulating cell growth and proliferation, and mTOR could activate the downstream protein effector. PTEN could negatively regulate mTOR
Liang WANG +5 more
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Zhongguo shiyan zhenduanxue, 2016 目的探讨五种血清肿瘤标志物癌胚抗原（CEA）、糖类抗原125（CA125）、神经元特异性烯醇化酶（NSE）、细胞角蛋白19片段（CYFRA21-1）及鳞状细胞癌相关抗原（SCC）检测对肺癌临床诊断的价值。方法采用电化学发光法检测血清中CEA、CA125、NSE、CYFRA21-1及化学发光法检测SCC的水平,比较分析五种血清学肿瘤标志物在肺癌临床诊断中的价值。结果试验中5种肿瘤标志物均能很好的鉴别肺癌患者与健康人群;CA125在诊断肺癌与其它肿瘤显著（AUC=0.706 ...
陈超 +4 more
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Analysis of Differentially Expressed Proteins in Self-Paired Sera of Advanced Non-small Cell Lung Cancer Patients Responsive to Gefin [PDF]
, 2009 Background and objective All the advanced NSCLC patients that received EGFR-TKI therapy will eventually relapse after a period of efficacy. The aim of this study is to investigate the serum biomarkers as potential predictive factors for the efficacy of ...
Ailin GUO +10 more
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Zhongguo shiyan zhenduanxue, 2012 本研究探讨增殖细胞核抗原（Proliferating Cell Nuclear Antigen,PCNA）与Mina53在非小细胞肺癌中的表达极其与放疗患者疗效的相关性,从而为早期预测非小细胞肺癌放疗敏感性提供依据,现报道如下。1资料与方法1 ...
赵光日
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The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
, 2009 Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
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Zhongguo shiyan zhenduanxue, 2012 非小细胞肺癌（non-small cell lung cancer,NSCLC）约占肺癌总数的75%-80%[1],随着社会工业化的不断发展和人口的老龄化,不同年龄段肺癌从发病因素和临床诊断各方面呈现出新的特点。本文收集了自2005年至2011年我院胸外科收治的1500例非小细胞肺癌患者的临床资料 ...
焦宏博, 李长锋, 李丹丹, 辛华
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The Expressions of IL-7 and IL-7R and the Relationship between them with Lymph Node Metastasis and Prognosis in Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective It has been proven that lymph node metastasis was closely related to prognosis of lung cancer. Interleukin-7 (IL-7) and interleukin-7 receptor (IL-7R) could promote lymph node metastasis through vascular endothelial growth factor-
Jian MING +4 more
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Zhongguo shiyan zhenduanxue, 2019 肺癌(lung cancer,LC)作为全球最常见的恶性肿瘤[1],病理分型包括小细胞肺癌(small cell lung cancer,SCLC)和非小细胞肺癌(non-small cell lung cancer,NSCLC)[2],非小细胞肺癌约占所有肺癌80%[3,4]。研究表明,吸烟、喝酒、遗传因素及环境污染等均是诱发NSCLC的重要因素[3,5]。通常,手术、生物疗法或放/化疗是治疗NSCLC的主要方法[6]。然而 ...
冯为
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Zhongshan Daxue xuebao. Yixue kexue ban, 2020 【目的】探究miR-204-3p 靶向EphB2 基因对非小细胞肺癌增殖、凋亡、侵袭的调控机制。【方法】培养将非小细胞肺癌A549 细胞系分为 5 组 NC mimic 组（miR-204-3p 过表达阴性对照组）、miR-204-3p mimic 组（miR-204-3p 过表达组）、oe-NC 组（EphB2 过表达阴性对照组）、oe-EphB2 组（EphB2 过表达组）、miR-204-3p mimic+oe-EphB2 组（miR-204-3p 与EphB2 均过表达组）。MTT、流式细胞术 ...
谢传华 +7 more
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Initial translational research from glucose metabolism molecular imaging of non-small cell lung cancer to PDTX models [PDF]
, 2017 第一部分18F-FDGPET/CT引导下骨转移灶靶向活检术在晚期 肺癌中的应用 目的：对于临床怀疑晚期肺癌需作诊断性活检时，穿刺活检部位选择前应借助于18F-FDGPET/CT的分期诊断。本研究的目的是评估18F-FDGPET/CT引导下晚期肺癌骨转移灶穿刺活检术的安全性和有效性及其在晚期肺癌靶向治疗中的临床应用价值。 方法:收集2013年1月至2015年9月在本PET中心做过18F-FDGPET/CT全身显像诊断为肺癌伴骨转移的病人，并在18F-FDGPET ...
郭崴
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