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Research Progress on Machine Learning Assisted Non-Targeted Screening Strategy for Identification of Fentanyl Analogs [PDF]
, 2023 In recent years, the types and quantities of fentanyl analogs have increased rapidly. It has become a hotspot in the illicit drug control field of how to quickly identify novel fentanyl analogs and to shorten the blank regulatory period.
Yu-qi CAO, Yan SHI, Ping XIANG, Yin-long GUO
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Developmental Medicine &Child Neurology, Volume 63, Issue 8, Page e1-e4, August 2021., 2021 目的 探討全基因體定序 (WGS) 對兒童神經疾病的診斷率及治療影響。 方法 從 2016 年 1 月至 2019 年 12 月, 使用全基因體定序對疑似患有遺傳性神經疾病的兒科病人進行評估。符合條件的病人依其臨床表現型分為四組: 神經發展障礙病人、癲癇病人、神經肌肉疾病病人及運動障礙病人。我們描述全基因體定序的診斷率及經全基因體定序確診後對病人治療的影響。 結果 共有 214 例病人 (男性 128 例, 女性 86 例) 接受了全基因體定序檢測, 病人平均 (SD) 發病年齡為 13.8 (27.6) 個月, 範圍為 1 天至 15 年 5 個月, 接受全基因體定序檢測的平均 (SD) 年齡為 71.7 (58.9) 個月, 範圍從 8 天到 18 歲。 43.9 ...
李 秀芬, 遲景 上, 蔡 啟仁
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Considerations on the development of national surveillance on food contaminants and harmful factors in China [PDF]
, 2020 Food safety is one of the most important technical support for Healthy China. The surveillance of food contaminants and harmful factors is the most important technical basis in the whole food safety management in China.
Dajin YANG, Ning LI
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Discriminant Analysis of Jiang-Flavor Baijiu of Different Grades by Gas Chromatography-Mass Spectrometry and Electronic Tongue [PDF]
, 2023 Gas chromatography-mass spectrometry (GC-MS) and electronic tongue were used to quantitatively determine the volatile compounds and taste indices of 21 Jiang-flavor baijiu samples of different grades.
LIN Xianli, ZHANG Xiaojuan, LI Chen, CHAI Lijuan, LU Zhenming, XU Hongyu, WANG Songtao, ZHANG Suyi, SHEN Caihong, SHI Jingsong, XU Zhenghong
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中西医结合护理, 2023 Objective To reduce the incidence of blood return in indwelling needle placement by targeted training based on Quality Control Circle (QCC) activity.
LI Xin (李欣) +4 more
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The Oncologist, Volume 24, Issue 12, Page e1437-e1442, December 2019., 2019 Abstract Testicular cancer is one of the few tumor types that have not yet benefited from targeted therapy. Still no new active agents for treating this cancer have been identified over the past 15 years. Once patients are refractory to cisplatin‐based chemotherapy, they will be expected to die from testicular cancer.
Bijun Lian +14 more
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LINC00665通过靶向miR-138/AKT1促进Hela细胞增殖和抑制凋亡的机制研究
Zhongguo shiyan zhenduanxue, 2021 目的探究长链非编码RNA LINC00665通过靶向微小RNA(microRNA,miR)-138/AKT1促进Hela细胞增殖和抑制凋亡的机制。方法分析TCGA数据库中宫颈癌患者miR-138水平与生存之间的关系。通过双荧光素酶报告验证LINC00665靶向miR-138和miR-138靶向AKT1。将宫颈癌细胞系Hela分为4组:对照组、mimic组、mimic+LINC00665组和LINC00665组,通过质粒转染技术过表达miR-138和/或LINC00665。分别通过qPCR和Western
刘晓娟, 谢双双, 张晶, 康燕华
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探讨肺癌脊柱转移瘤患者的手术疗效及影响患者生存期的预后因素。方法随访2013年3月至2020年5月于中山大学孙逸仙纪念医院接受诊治的156例肺癌脊柱转移瘤患者，根据纳入与排除标准，36例患者的病例资料入选本研究进行后续分析。根据治疗方式将患者分为手术治疗组（n=26）和保守治疗组（n=10），分别采用视觉疼痛评分（VAS评分）、卡氏日常功能状态评分（KPS评分）及Frankel分级对患者治疗前后的疼痛程度、功能状态和脊髓神经功能进行评估，采用 Kaplan-Meier 法绘制生存曲线 ...
李玉希 +7 more
doaj
Progress in the 16S rRNA Gene Sequencing in Forensic Science [PDF]
, 2018 Forensic microorganism is one of the hotspots of forensic science research. Due to its conservatism and specificity, the 16S rRNA gene is found to be an ideal marker for forensic identification.
SONG Guo-qing, CAO Yu, LI Hui，et al.
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Research Progress in the Application of Gas Chromatography-Ion Mobility Spectrometry in Food Authentication [PDF]
Gas chromatography-ion mobility spectrometry (GC-IMS) is a sensitive analytical technology for the detection, identification and monitoring of trace substances in different matrices, which enables secondary rapid separation and high-precision qualitative
ZHANG Biying, SUI Yumeng, ZHANG Xin, LI Yongjie, KONG Baohua, LIU Haotian, CHEN Qian
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