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结直肠癌患者尿液中20种氨基酸靶向代谢组特征研究 附视频

Zhongguo shiyan zhenduanxue
目的 探究20种常见氨基酸在结直肠癌(CRC)患者的尿液特征；寻找CRC诊断的生物学标志物。方法 纳入100名健康对照者和113名CRC患者(Ⅰ期27例，Ⅱ期28例，Ⅲ期34例，Ⅳ期24例),基于超高效液相色谱串联质谱法对尿液中的20种常见氨基酸应用多反应监测技术进行靶向定量分析，应用统计学方法分析CRC患者与健康对照氨基酸含量差异，并构建CRC诊断模型。结果 CRC患者尿液中16种氨基酸含量与健康对照差异有统计学意义，Ⅰ,Ⅱ,Ⅲ和Ⅳ期各自有9种，15种，14种 ...
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[Transcriptomic characteristics of cervical endplate cartilage in cervical spondylosis and effects of acupotomy on the FGF18/Akt axis with cervical spondylosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu F, Khaliunaa T, Cao Q, Yang Y, Ren C, Zhu J, Zhao X, Cao L, Deng B, Wang X.   +9 more
europepmc   +1 more source

[Exposures to volatile organic compounds are positively correlated with risks of metabolic dysfunction-associated steatotic liver disease]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li K, Zeng W, Zhang Y, Zhu X, Guo B.
europepmc   +1 more source

[Mechanism of Eclipta prostrata L-Ligustrum lucidum Ait in the treatment of periodontitis]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Guo M, Zhang T, Huang J, Huang X, Zheng Y, Zhang L.   +5 more
europepmc   +1 more source

[Clinical characteristics and prognostic analysis of pediatric acute myeloid leukemia with -7/7q- abnormalities]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zheng FY, Wang M, Ding MM, Lu AD, Jia YP, Zeng HM, Zhang LP.   +6 more
europepmc   +1 more source

[Rosa laevigata Michx. inhibits pulmonary arterial smooth muscle cell proliferation in hypertension by modulating the Src-AKT1 axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yang Z, Lü C, Dong Z, Ji S, Bi S, Zhang X, Wang X.   +6 more
europepmc   +1 more source

[A heterogeneous graph method integrating multi-layer semantics and topological information for improving drug-target interaction prediction]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Chen Z, Guo Y, Song S, Guo Q, Zhou D.
europepmc   +1 more source

[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao B, Lü Z, Ji D, Tian S, Wu Y, Li X, Zhou J, Fang J, Liang Y.   +8 more
europepmc   +1 more source

[Comparison of setup errors between two immobilization methods in prostate cancer radiotherapy based on cone-beam computed tomography]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Liu J, Ma M, Wang Q, Shi M, Yin J, Wang Z, Shen J, Gao X.   +7 more
europepmc   +1 more source

[The role and molecular mechanism of transcription factor EB and its target genes in multiple myeloma treatment with bortezomib]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang RJ, Wang ZL, Shi XM, Zhang SY, Wang W, Ma MS, Li C, Gu CH, Zhang ZH.   +8 more
europepmc   +1 more source