Recent Progress in the Application of High Resolution Mass Spectrometry for Screening Migrating Substances from Food Contact Materials [PDF]
Due to the lack of detection methods, mass spectral databases and reference standards, identifying migrating substances from food contact materials (FCMs) that have wide variations in migration concentrations, high varietal diversity, and complex ...
WANG Guoxiu, ZHANG Qi, LU Jia, WANG Zhaohui, DU Zhenxia
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Application of Gas Chromatography-Ion Mobility Spectroscopy for Honey Quality Evaluation [PDF]
Honey is rich in nutrients and has a wide range of biological activities. However, due to the different botanical origins, geographical origins, entomological origins, and maturity, honey shows significant differences in their endogenous compositions and
Daoqi LONG +7 more
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, EarlyView.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
NMR-based metabolomic analysis of Haliotis diversicolor in response to different environmental stressors [PDF]
, 2016 在过去的十几年中，代谢组学已经取得了巨大的进步，为复杂生物系统的研究提供了一种可靠且高通量的分析方法。代谢组学方法也越来越多地用于研究生物有机体与生态环境之间的相互作用。近年来，该方法已被广泛应用于环境评价和野生动物的疾病诊断，成为环境科学领域中充满活力的研究方向之一。 杂色鲍（Haliotisdiversicolor）是中国南方沿海地区一种重要的经济养殖贝类，同时对环境变化非常敏感，是一种理想的海洋环境监测指示生物。本论文以杂色鲍为研究对象，利用基于1HNMR波谱与模式识别方法 ...
卢洁
core
Research Progress on the Ecological Risk Status and Analytical Techniques of Per- and Polyfluoroalkyl Substances [PDF]
This paper is a review of the current state of pollution and analytical techniques for per- and polyfluoroalkyl substances (PFASs) in various environmental media.
Hongtao WANG, Weijie WANG
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Research progress of non-invasive neuromodulation techniques in the treatment of posttraumatic stress disorder [PDF]
Post-traumatic stress disorder (PTSD) can lead to impaired functions such as attention, memory, and executive function, and trigger abnormal brain activity as well as disrupted functional connectivity between brain regions.
Changjian QIU +3 more
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The Latest Research Progress on Cell-Free DNA and Prospects of Its Forensic Application [PDF]
In recent years， with the continuous progress of DNA extraction and detection technology， cell-free DNA（cfDNA）has been widely used in the life science field， and its potential application value in forensic identification is becoming more and more obvious.
Wen-jing HU, Ting-ting YANG, Ya-ya WANG, Jiang-wei YAN
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lncRNA PROX1-AS1负调控miR-206对鼻咽癌细胞SUNE1增殖、迁移侵袭的影响
Zhongguo shiyan zhenduanxue, 2021 目的探讨长链非编码RNA(lncRNA)PROX1反义RNA1(PROX1-AS1)是否靶向miR-206影响鼻咽癌细胞SUNE1的增殖、迁移和侵袭。方法采用实时定量PCR(RT-qPCR)检测鼻咽癌组织和癌旁组织中PROX1-AS1和miR-206表达。双荧光素酶报告实验和RT-qPCR分析PROX1-AS1和miR-206靶向关系。细胞计数试剂盒(CCK-8)法、克隆形成实验、Transwell实验检测PROX1-AS1和miR-206表达对SUNE1细胞增殖活力、克隆形成数、迁移和侵袭细胞数的影响。
袁小卫, 王彦君, 熊健, 何学祥
doaj
Preparation of Folate Receptor Targeted Gold Nanoparticles and Application Research in Cancer Cells Detection [PDF]
, 2010 纳米金由于具有独特的理化性质及良好的生物亲和效应，不仅在催化、自组装、微电子、传感器等领域表现出广阔的应用前景，在生物医学领域，如生物标记、生物检测、药物传输等方面也有重要的潜在应用价值，因此受到越来越广泛的关注。本文采用两种不同的方式制备了叶酸受体靶向型纳米金颗粒，并探讨了它们的物理化学性质、生物相容性以及对癌细胞的靶向和检测性能。 谷胱甘肽偶联法以柠檬酸钠为还原剂，用微波水热法制备出粒径均一、分散性好的纳米金（GNPs），然后纳米金与谷胱甘肽（GSH）的巯基作用，形成GSH修饰的纳米金（GSH ...
张召武
core
Pifu-xingbing zhenliaoxue zazhi[目的] 分析神经梅毒患者的脑脊液代谢物，以确定潜在的诊断标志物。 [方法] 利用液相色谱-质谱联用技术的非靶向代谢组学，分析5例神经梅毒患者和5例梅毒/非神经梅毒患者的脑脊液样本。将原始数据经过质量控制和归一化处理后，进行数据分析（主成分分析、正交偏最小二乘判别分析、层次聚类分析）确定两组间的差异代谢物。 [结果] 神经梅毒患者体内，有6种代谢物显著升高，分别是Pro-leu、nudifloramide、N-oleoyl glycine、DMP 777 ...
贺 媛媛 +5 more
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