Results 11 to 20 of about 87 (81)
Factors Associated with Thrombosis in Primary Immune Thrombocytopenia [PDF]
BackgroundPatients with primary immune thrombocytopenia (ITP) , a hemorrhagic disease characterized by thrombocytopenia, have increased incidence of thrombotic events, which increases the treatment difficulty.
YANG Shuo, WANG Yong, CHEN Shuxia, ZHAO Mingfeng
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The latest progress and prospect of gynecological tumor treatment at 2023 ESMO [PDF]
Many major research achievements have been made in the past year in the field of gynecologic oncology (cervical cancer, ovarian cancer and endometrial cancer), including surgical treatment, local advanced treatment mode and exploration of new treatments ...
XIA Lingfang, ZHU Jun, WU Xiaohua
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To review the clinical data of a patient with myelodysplastic syndrome and summarize the experience of treatment and nursing under the integrated mode of medical care.
MA Huigai (马会改) +2 more
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Chinese arsenic drugs have been applied in Chinese medicine for several centuries. Active ingredients of realgar is As2S2. Oral realgar has been widely used in the treatment of myelodysplastic syndrome (MDS) with obvious Chinese characteristics, and the ...
Deng, Zhong-yang +2 more
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Clinical analysis of 103 cases of invasive pulmonary fungal infection [PDF]
目的 分析侵袭性肺部真菌感染(IPFI)的临床特点,探讨防治对策。方法 对103例IPFI的临床资料进行回顾性分析。结果 IPFI以COPD、支气管肺癌多见,滥用抗生素等是主要危险因素;念珠菌属占57.3%,其次为曲霉菌属占32.0%;病死率为20.4%。结论 IPFI是在多种诱发因素下继发的肺部感染,原发性IPFI少见;其病死率高,重视易患因素的控制、尽早诊断,综合治疗可降低死亡率。Objective: To analyze the clinical features of invasive ...
Zeng, Zhi-ping, Zhang, Zu-ping
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未经治疗的CLL与MT2A-ELL融合突变的AML双重白血病1例
慢性淋巴细胞白血病(Chronic lymphocytic leukemia,CLL)是一种成熟的B细胞肿瘤,可引起患者的免疫抑制状态,增加其他类型癌症的发生率。根据以往研究,与一般人群相比,CLL患者同时发生恶性肿瘤(如肺癌、黑色素瘤等)的风险更高[1]。除了发展成实体瘤外,CLL患者易并发多发性骨髓瘤[2-3],骨髓增生异常综合征(MDS)和急性髓系白血病(AML)。然而,自20世纪70年代以来,只有数十例CLL并发其他血液系统恶性肿瘤的报道[4-8]。
张诗林 +4 more
doaj
A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia [PDF]
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 ...
HAO Siguo, HUANG Fang, LIU Jiayu
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Practice and Experience of Clinical Pharmacists Participating in the Treatment of 2 Cases of Atypical Pathogens Infection [PDF]
目的:探讨临床药师参与2例非典型病原体感染会诊的思维和方法。方法:对2例非典型病原体感染会诊案例进行分析,总结归纳会诊经验。结果:会诊后,2例患者治疗效果明显。结论:临床药师可协助医师提高药物治疗有效性和安全性。Objective: To investigate the thoughts and methods of clinical pharmacists involving in the treatment of 2 cases of atypical pathogen infection ...
张云琛, 戴成家, 王芳芳, 费燕
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骨髓增生异常综合征(MDS)是血液系统的恶性疾病,常常伴有血液系统细胞不同程度的贫血而需要输血。国内外均有报导骨髓增生异常综合征疾病在发生发展过程中,患者的血型抗原可能减弱或丢失或抗体效价降低的情况[1,2],故血型的正确鉴定是确保患者安全输血的前提。1材料与方法1.1样本收集2009年2月~2011年3月在本院住院诊断为骨髓增生异常综合征患者28例,其中男性17人,女性11人,年龄35~62岁 ...
蒿广德, 刘敏, 齐文玲, 蒲丽蓉
doaj
hnRNPA2/B1 regulates apoptosis-related gene PLK3 expression and BIM alternative splicing in breast cancer cells [PDF]
目的:核糖核不均一蛋白(hnRNPA2/B1)作为一个可变剪切子,在乳腺癌组织中过度表达,参与细胞多种生理过程。本文研究乳腺癌细胞中hnRNPA2/B1调控凋亡相关基因PLK3表达和BIM的可变剪切。 方法:通过CRISPSR-Cas9技术敲除乳腺癌细胞MCF-7和MDA-MB-231中hnRNPA2/B1基因后,验证凋亡相关基因的表达;结合转录组测序分析以及RTPCR验证凋亡相关基因是否发生可变剪切,并通过RNA免疫沉淀技术检测hnRNPA2/B1蛋白是否与凋亡相关基因的pre-mRNA结合 ...
李龙
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