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强化免疫抑制治疗儿童再生障碍性贫血疗效分析

Zhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】探讨强化免疫抑制治疗儿童再生障碍性贫血的疗效及毒副作用的防治。【方法】总结我科1996—2003年儿童再障32例,均采用强化免疫抑制治疗(IIST),根据免疫抑制药物的不同组合分为2组:4种药物联合组和2～3种药物联合组。【结果】总有效率为71.88%,4种药物联合组、2～3种药物联合组有效率分别为72.2%及71.33%,差别无显著性。治疗过程中,致命的合并症为败血症,尤其潜伏病毒激活及深部真菌感染。随访中没有病例发展为阵发性睡眠性血红蛋白尿(PNH),骨髓异常增生综合征(MDS ...
doaj  

[Application of the variant allele frequency of myeloid-associated gene mutations in myelodysplastic syndrome]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Shang MY, Su L.
europepmc   +1 more source

[Avapritinib for systemic mastocytosis with an associated myelodysplastic/myeloproliferative neoplasm: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Tang YW, Pan LJ, Li FH, Xiao ZJ, Xu ZF.
europepmc   +1 more source

[The value of WT1 mRNA expression level in the diagnosis and prognosis evaluation of myelodysplastic syndromes]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Li B, Li P, Miao M, Chen SN, Xiao ZJ.
europepmc   +1 more source

How epigenetics can explain human metastasis A new role for microRNAs [PDF]

, 2009
Amaia Lujambio, Manel Esteller
core  

[Long-term hypomethylating agents in patients with myelodysplastic syndromes: a multi-center retrospective study]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Liu XZ, Zhou SJ, Huang J, Zhao CF, Jiang LX, Zhang YD, Mei C, Ma LY, Zhou XP, Shao YP, Wu GQ, Xiao XB, Yao RX, Du XH, Hu TL, Qian SX, Li Y, Yan XF, Huang L, Wang ML, Fu JP, Shou LH, Jiang WH, Jin WM, Li LJ, Le J, Luo WJ, Zhang Y, Zhou XJ, Zhang H, Lang XH, Zhou M, Jin J, Jiang HF, Zhang J, Ouyang GF, Tong HY.   +36 more
europepmc   +1 more source

[Progress in pre-myelodysplastic syndrome conditions]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2020
Zhang W, Fu R.
europepmc   +1 more source

[Analysis of the association between pre- and post-treatment genetic mutation status and treatment efficacy and survival in patients with newly diagnosed myelodysplastic syndromes with excess blasts receiving hypomethylating agent therapy]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhong T, Qin TJ, Xu ZF, Pan LJ, Qu SQ, Jiao M, Gao QY, Xiao ZJ, Li B.   +8 more
europepmc   +1 more source

[Clinical characteristics and prognosis of patients with myelodysplastic syndrome with a bone marrow nucleated erythroid cell proportion of greater than or equal to 50]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zeng YP, Li B, Qin TJ, Xu ZF, Qu SJ, Pan LJ, Gao QY, Jiao M, Wu JY, Wang HJ, Li CW, Ja YJ, Sun Q, Xiao ZJ.   +13 more
europepmc   +1 more source

[Clinical significance of IL-18 and IL-18-binding protein in bone marrow of patients with myelodysplastic syndrome]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Wang T, Ran NY, Chen QL, Liu DL, Zang MT, Li NB, He X, Guan J, Fu R, Shao ZH.   +9 more
europepmc   +1 more source