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中西医结合护理, 2023 Objective To investigate the effect of collateral-dredging tendon-strengthening exercise on postoperative rehabilitation of patients undergoing spinal surgery.
ZHU Fengxiang (朱凤祥) +2 more
doaj +1 more source
Journal of Diabetes, Volume 15, Issue 4, Page 332-337, April 2023., 2023 Abstract Background Diabetic foot infection, particularly osteomyelitis, is a major risk factor of amputation in persons with diabetes. Bone biopsy with microbial examination is considered the gold standard of diagnosis of osteomyelitis, providing information about the offending pathogens as well as their antibiotics susceptibility.
Hassan Al‐Balas +3 more
wiley +1 more source
Wireless Communications and Mobile Computing, Volume 2021, Issue 1, 2021., 2021 Clinical named entity recognition (CNER) identifies entities from unstructured medical records and classifies them into predefined categories. It is of great significance for follow‐up clinical studies. Most of the existing CNER methods fail to give enough thought to Chinese radical‐level characteristics and the specialty of the Chinese field.
Yue Wu +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2022 随着人年龄的改变，人体内的骨髓也会逐渐发生着改变，会逐渐由脂肪含量较少的红骨髓变为脂肪含量较高的黄骨髓，并且骨髓中的水含量、蛋白质含量以及骨髓的造血功能也发生着改变，这种骨髓转换的生理现象大约会在25～30岁左右结束[1-3]。成年健康人中大部分的造血活性骨髓是分布在低位腰椎、骶骨、髂骨及股骨近端，因而骨盆骨髓便是主要的造血点，骨盆骨髓中含有较多增殖分化快的造血细胞，因此对辐射具有高度敏感性[4-6]。
陈贵南 +3 more
doaj
Unsupervised Medical Entity Recognition and Linking in Chinese Online Medical Text
Journal of Healthcare Engineering, Volume 2018, Issue 1, 2018., 2018 Online medical text is full of references to medical entities (MEs), which are valuable in many applications, including medical knowledge‐based (KB) construction, decision support systems, and the treatment of diseases. However, the diverse and ambiguous nature of the surface forms gives rise to a great difficulty for ME identification.
Jing Xu +4 more
wiley +1 more source
The experimental research of "two steps" bone tissue engineering treatment in rabbit radial defect [PDF]
, 2015 目的:探讨等量骨髓富集液与脱钙骨基质（DBM）复合，一次植入与分次植入修复骨缺损效果是否存在差异。验证骨髓富集方法有效性。 方法:一步法组（A组），即在手术时将5ml骨髓进行富集，将富集液和DBM复合一期植入，一周后不再打入骨髓富集液，仅打入PBS溶液。二次注射组（B组），一期手术时植入单纯DBM，一周后注射5ml骨髓的富集液。分步注射组（C组），在手术时将2.5ml骨髓进行富集，将富集液和DBM复合一期植入，一周后再打入2.5ml骨髓富集液。纯空白对照组（D组），植入单纯DBM材料，不加入骨髓富集液 ...
刘奎生
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The role of hedgehog pathway and autophagy in the mechanism of acquired chemoresistance in multiple myeloma [PDF]
, 2015 在多发性骨髓瘤的临床治疗中，化疗耐药现象仍然是治疗失败的主要原因之一。为了更好地了解多发性骨髓瘤的化疗耐药性及相关的机制，我们建立了阿霉素(doxorubicin,DOX)耐药的细胞系多发性骨髓瘤细胞系RPMI8226/R（doxorubicin-resistantcellline），DOX对8226/R的半数抑制率(IC50)是对DOX敏感的细胞系RPMI8226/S（chemosensitivecellline）的5~6倍。我们发现在多发性骨髓瘤耐药性的诱导过程中存在Hedgehog(Hh ...
黄潇
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Experimental study on effect of bone marrow mesenchymal stem cells on the function of severe fatty liver graft [PDF]
, 2015 第一章：大鼠骨髓间充质干细胞的分离、培养与鉴定 目的体外培养活性好、纯度高的骨髓间充质干细胞 方法采用密度梯度离心法分离培养骨髓间充质干细胞，采用流式细胞仪鉴定其表面抗原的表达情况，用成软骨试剂、成脂试剂诱导BMSCs分化成软骨细胞、脂肪细胞。 结果获得细胞具有明显的贴壁性，其细胞表面高表达CD44、CD90、CD29抗原分子，低表达CD45、CD34、CD11b抗原分子。成软骨诱导分化3周，BMSCs即可分化成软骨细胞，成脂诱导分化2周，即可分化成脂肪细胞。 结论密度梯度离心法可以获得活性好、纯度高 ...
范洪凯
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Functions of Periostin in pre-metastatic immunosuppressive niches of breast tumor metastasis [PDF]
, 2016 在肿瘤发生发展过程中，肿瘤细胞及其相关间质细胞向肿瘤微环境中分泌大量促癌细胞因子以及趋化因子，促使骨髓来源的免疫抑制细胞（myeloid-derivedsuppressorcells，MDSCs）向远处靶器官浸润，形成免疫抑制微环境，为肿瘤细胞的转移提供有利条件，从而促进肿瘤细胞的转移。在乳腺癌肿瘤组织中，细胞外基质蛋白Periostin主要由肿瘤相关成纤维细胞分泌，并参与调控肿瘤的发生发展过程。然而，关于Periostin蛋白在MDSCs介导的转移前微环境形成中的功能尚不清楚 ...
熊珊珊
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The research of developing functional artery with collateral circulation in the ischemic hindlimb [PDF]
, 2016 1、背景与目的 随着社会的发展，血管方面疾病的发病率呈现日益增高的趋势。在众多血管疾病中动脉硬化闭塞症、血栓闭塞性脉管炎等这一类疾病均可能伴随出现下肢缺血的症状。其中手术治疗主要包括人造血管旁路移植、支架植入以及球囊成形术等，但血管移植通常会形成血栓而只有短期的通畅性，支架植入和血管成形术往往又会造成扩张部位的再狭窄。对于血管病变广泛而无法进行手术或腔内治疗的患者，就只能通过药物保守治疗，通常是采用扩血管、抗凝和抗血小板等方法来改善其血液供应，随着病程的发展，药物往往不能起到很好的效果 ...
周旭
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