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Clinical study on high-risk factors for contralateral lymph node metastasis in unilateral papillary thyroid carcinoma [PDF]
Background and purpose: The occurrence of lymph node metastasis in papillary thyroid cancer (PTC) can have adverse effects on the prognosis of patients. This study aimed to investigate risk factors related to the occurrence of contralateral central lymph
YUAN Xinyue, YAO Yao, CHENG Shuai, ZHENG Xin, ZHANG Yuan
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目的 分析首次青年缺血性卒中患者出院、发病90d预后不良的相关危险因素。 方法 回顾性纳入18~45岁、发病72 h内的首次缺血性卒中患者,收集患者人口学信息、血管危险因素、实验室检查结果、入院和出院时NIHSS,以出院时和发病90 d mRS≥2分为预后不良,分别比较预后不良组和预后良好组危险因素的差异和病因分型特点,并采用多因素logistic回归分析出院和90 d预后不良的独立危险因素。 结果 研究共纳入691例首次青年缺血性卒中患者,出院预后不良234例(33.9%),90 ...
刘艳芳, 贾娇坤, 赵性泉
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Associated Risk Factors in Group B Streptococcus Infection During Pregnancy [PDF]
BackgroundGroup B streptococcus (GBS) infection can give rise to intrauterine infection during pregnancy and postpartum endometritis, and increase the risk of premature birth or stillbirth.
HUANG Yan, WANG Mingying, FENG Junyan, ZHANG Jie
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New concept of de-escalation management strategy in breast cancer patients with 1-2 positive sentinel lymph nodes [PDF]
In the era of sentinel lymph node biopsy (SLNB), the axillary management concept that 1-2 positive sentinel lymph node (SLN) could safely omit axillary lymph node dissection (ALND) are gradually being accepted by more and more patients.
BI Zhao, WANG Yongsheng
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The Value of Handheld COPD-6 Spirometry for Early COPD Detection in High Risk Elderly Population in Community [PDF]
BackgroundChronic obstructive pulmonary disease (COPD) is a common chronic disease of the respiratory tract, and lung function is necessary for the diagnosis of COPD.
XU Yunli, SHAO Hongtao, REN Xiaohong, LIU Lilan
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FoxO3 Inactivation Promotes Human Cholangiocarcinoma Tumorigenesis and Chemoresistance through Keap1-Nrf2 Signaling [PDF]
许多人类肿瘤中存在PI3K/AKT过度激活,然而该通路的异常导致肿瘤形成的分子机理仍未充分阐明。FoxOs是受PI3K/AKT负向调控的转录因子,与肿瘤形成密切相关,但对于FoxOs调控肿瘤生长的机制尚不十分清楚。胆管癌是一类起源于胆道上皮细胞的恶性肿瘤,胆管癌患者对化疗敏感性差,但耐药机理尚未充分阐明。Nrf2的激活与胆管癌耐药性及病人不良预后密切相关。高度激活的PI3K/AKT能够激活Nrf2信号通路,但其中具体的分子机制尚不清楚。Keap1是连接Nrf2与Cul3的衔接蛋白 ...
管丽
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Analysis of high risk factors of pathological escalation after LEEP in CIN2 diagnosed by colposcopic biopsy [PDF]
Objective To investigate the risk factors associated with pathological escalation to cervical intraepithelial neoplasia grade 2 (CIN2) or above (CIN2+) in patients with CIN2 confirmed by colposcopic biopsy, aiming to provide evidence for the stratified ...
Ma Xiaoli, Meng Ge, Duan Hua
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目的探讨双胎早产与单胎早产高危因素的特点以及单、双胎早产儿的结局。方法回顾性分析广州医科大学附属第三医院2009年1月至2015年12月的单、双胎孕产妇与新生儿临床数据资料。结果研究期间在该院分娩的36 931例新生儿,双胎2080例,单胎34 851例,其中早产5877例,双胎早产1395例(双胎早产组),早产率为67.07%;单胎早产4482例(单胎早产组),单胎早产率为12.86%,总计早产发生率为15.91%,双胎早产率明显高于单胎,差异有统计学意义(P22~26岁组、>26~30岁组、>30 ...
余波澜 +7 more
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目的 探讨肾移植患者发生全麻苏醒期高血压危象的影响因素。方法 回顾性分析2019年9月—2021年9月期间吉林大学第一医院进行的98例急诊同种异体肾移植手术的临床资料。根据麻醉苏醒期的血压分为高血压危象组(49例)和血压稳定组(49例),对比两组的临床资料并分析肾移植患者发生全麻苏醒期高血压危象的影响因素。结果 高血压危象组与血压稳定组相比,前者平均年龄较大、BMI值较高、受体存在原发性高血压的比例较大、高血压脑出血供肾的比例较大、T1和T2时的收缩压较高 ...
段文燕 +3 more
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目的探讨急诊剖宫产术后切口感染的危险因素。方法选取2017年1月-2019年1月德州市妇女儿童医院急诊剖宫产术后的患者150例,调取临床病例信息及一般临床资料,使用Logistic回归分析筛选急诊剖宫产术后切口感染的独立危险因素。结果通过对急诊剖宫产术后感染的危险因素单因素分析得出,两组患者的年龄、剖宫产史、产次和妊娠期糖尿病无明显差异(P>0.05),高血压、高血糖、肥胖、胎膜早破、双胎、术中出血量和手术时间具有明显差异 ...
史扬 +6 more
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