Results 11 to 20 of about 4,617 (172)

Insulin resistance is associated with urinary albumin‐creatinine ratio in normal weight individuals with hypertension and diabetes: The REACTION study 胰岛素抵抗与尿白蛋白肌酐比值在体重指数正常的高血压合并糖尿病人群中相关:中国REACTION研究

open access: yesJournal of Diabetes, Volume 12, Issue 5, Page 406-416, May 2020., 2020
Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu   +4 more
wiley   +1 more source

Pre‐existing type 2 diabetes is an adverse prognostic factor in patients with renal cell carcinoma 2型糖尿病是肾细胞癌患者的不良预后因素

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 993-1001, December 2019., 2019
Highlights Type 2 diabetes (T2D) is an independent predictor of survival and recurrence after surgery in patients with renal cell carcinoma (RCC). This finding reveals the importance of T2D in determining the prognosis of patients with RCC. Abstract Background Diabetes is a risk factor for various cancers, but its prognostic role in renal cell ...
Haosen Yang   +8 more
wiley   +1 more source

Review of glucagon‐like peptide‐1 receptor agonists for the treatment of type 2 diabetes mellitus in patients with chronic kidney disease and their renal effects 胰高血糖素样肽‐1受体激动剂治疗慢性肾脏病合并2型糖尿病患者及其对肾功能影响的研究进展

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 938-948, December 2019., 2019
Highlights Diabetic kidney disease is a common comorbidity of type 2 diabetes mellitus. In studies investigating the effect of renal function on the efficacy of treatment with glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), these agents improved glycemic control in patients with mild to moderately impaired kidney function, without significant ...
Lance A. Sloan
wiley   +1 more source

高血压所致肾损害患者临床及病理分析

open access: yesZhongguo shiyan zhenduanxue, 2021
高血压可以导致全身多个器官及系统的病变,其中肾脏是其损害的重要靶器官[1-2]。原发性高血压导致的肾脏损害主要体现为肾脏血管病变,称为良性肾小动脉硬化,晚期可见肾小球的萎缩及硬化,并最终导致肾功能完全丧失。而在肾脏功能受损的过程中,由于肾脏对水钠排泄障碍、血管内皮损伤因子增加、肾素-血管紧张素-醛固酮系统的激活等也可导致血压进一步增高。63%-90%的恶性高血压患者存在不同程度的肾脏结构和功能损害[3],且可快速发展至终末期肾脏病。
王淑平   +3 more
doaj  

Causes of death in patients undergoing maintenance hemodialysis a 10-year retrospective analysis in a single center [PDF]

open access: yes
Objective To retrospectively analyze the characteristics of maintenance hemodialysis (MHD) patients who have died in the past decade, with the aim of understanding the mortality rate, causes of death, and other factors in MHD patients. Methods A total of
YAN Junfang, WANG Deguang, WANG Ruifeng, LI Huai, YUAN Liang
core   +2 more sources

Correlation of FRAIL scale and fragile index with adverse outcomes in elderly patients on maintenance hemodialysis [PDF]

open access: yes
Objective To explore the FRAIL scale and fragile index (FI) and adverse outcomes of elderly maintenance hemodialysis (MHD) patients. Methods From June 2020 to December 2022, 116 elderly patients on MHD were selected and assigned into two groups of ...
Fang Jin, Li-qun Gao, Su-xia Wang
core   +1 more source

2 型糖尿病患者合并肾脏疾病的临床病理及预后 [PDF]

open access: yes, 2020
【目的】探讨 2 型糖尿病(T2DM)患者合并肾脏疾病的临床病理特点及预后。【方法】回顾性分析120 例尿检异常和(或)Scr 升高并接受肾活检的2 型糖尿病患者的临床病理资料,并进行了随访。肾脏结局的定义是接受肾脏替代治疗或进入到终末期肾病(ESRD)。Kaplan-Meier 分析用于比较肾存活率,Cox 比例风险分析用于进行糖尿病肾病(DN)和非糖尿病肾脏疾病(NDRD)进入 ESRD 的风险比较。【结果】120 例 2 型糖尿病患者中,肾穿刺确诊DN57 例,占47.5%;NDRD63 例 ...
叶增纯   +5 more
core  

阿魏酸钠联合厄贝沙坦对慢性肾功能衰竭患者血清炎性因子、Hcy、PTH及β2-MG的影响 [PDF]

open access: yes, 2019
目的探讨阿魏酸钠联合厄贝沙坦对慢性肾功能衰竭患者血清炎性因子、Hcy、PTH及β2-MG的影响。方法选取2016年3月~2017年5月我院收治的慢性肾功能衰竭患者100例,随机分为两组,对照组给予口服厄贝沙坦,研究组在对照组基础上加用阿魏酸钠静脉滴注进行治疗。观察并比较治疗1个月后两组患者治疗前后各项血清炎性因子、同型半胱氨酸(Hcy)、甲状旁腺素(PTH)及β2微球蛋白(β2-MG)等指标情况,观察并比较两组患者治疗过程中不良反应的发生情况。结果经治疗1个月后 ...
陈璐
core  

Relationship between aldose reductase、sodium/potassium/2 chloride cotransporter type 2(NKCC2)and serum and glucocorticoid inducible protein kinase(SGK) in renal cells [PDF]

open access: yes, 2008
糖尿病肾病(diabeticnephropathy,DN)是糖尿病慢性并发症(DCC)中的一种,它是糖尿病(DiabetesMellitus,DM)致死致残的主要原因。据统计,30%~40%的Ⅰ型糖尿病患者和40%的Ⅱ型糖尿病患者并发糖尿病肾病,可由最初出现蛋白尿发展到高血压、肾病综合症,最终导致肾衰和死亡,DN的3年生存率仅为50%左右。糖代谢的多元醇通路与糖尿病血管病变、肾脏病变、视网膜病变及外周神经病变等糖尿病慢性并发症密切相关。而醛糖还原酶(AldosereductaseAR ...
李劼
core  

集成磁共振成像技术评估COVID-19康复患者神经损伤 [PDF]

open access: yes
目的应用集成磁共振成像技术(SyMRI)评估COVID-19康复患者脑灰质微结构的改变。方法29例COVID-19康复患者分为重症患者组(SG=11例)和普通患者组(OG=18例),选取年龄、性别、体质指数(BMI)和教育年限相匹配的健康志愿者作为健康对照组(HC=23例)。所有受试者均行SyMRI扫描,生成T1、T2定量图谱,利用自动解剖标记(AAL)模板将T1和T2图谱分割成90个感兴趣区(ROIs)。通过对ROI内的所有体素进行平均得到每个ROI的T1、T2弛豫值。分析比较三组间90个脑区的T1 ...
吴文浩   +5 more
core   +1 more source

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