Results 61 to 70 of about 11,785 (168)

External validation of QUiPP App in three independent European cohorts of symptomatic women

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 2, Page 163-174, August 2025.
ABSTRACT Objective To validate externally the QUantitative Innovation in Predicting Preterm birth (QUiPP) App v.2 for the prediction of spontaneous preterm birth (sPTB) in symptomatic women attending tertiary care in Europe. Methods The QUiPP App v.2 was validated in three independent datasets: a prospective European multicenter cohort across five ...
A. M. Fischer   +8 more
wiley   +1 more source

基于Relief F和灰色关联分析的高压断路器机械故障诊断

open access: yesGaoya dianqi, 2020
为提升高压断路器机械故障诊断算法故障诊断效率与精度,文中提出一种基于Relief F算法和灰色关联分析的故障诊断方法。首先,从高压断路器分合闸线圈电流中提取20种特征量,采用Relief F算法计算所有特征权重;然后,使用基于重要特征构成的故障样本建立灰色关联分析模型的参考序列,并归一化对应特征权重向量;最后,计算参考序列与待测序列之间的关联度值确定待测样本故障类型。通过实例分析验证结果表明,文中提出的诊断方法能准确诊断高压断路器机械故障,同时引入Relief F算法降低诊断模型复杂度并提高故障诊断效率,
李邦彦   +8 more
doaj  

Study on the distribution and diversity of nanoflagellate in the Yangtze estuary and continental shelf of East China Sea [PDF]

open access: yes, 2015
本研究应用荧光显微技术、荧光标记颗粒示踪法以及Illumina高通量测序技术,分别于2013年春季、2013年夏季和2013年秋季开展了对长江口及东海陆架区微型鞭毛虫的丰度分布、异养细菌的摄食和群落多样性的研究,并初步探讨了影响微型鞭毛虫分布、摄食和群落多样性的因素。主要结果如下: (1)长江口及东海陆架区微型鞭毛虫的丰度变化范围为0.41-7.15×103cellsml-1,微型鞭毛虫丰度的最高值出现在夏季,最低值出现在秋季,表现出明显的季节变化特征 ...
吴林南
core  

Simple sequence repeats and their expansions: role in plant development, environmental response and adaptation

open access: yesNew Phytologist, Volume 247, Issue 2, Page 504-517, July 2025.
Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar   +3 more
wiley   +1 more source

Ecological Studies of Marine Virus and its Viral Lysate [PDF]

open access: yes, 2015
病毒是海洋生态系统中数量最多、多样性最为丰富的一类生命形式,具有极为重要的生态地位。为了深入认识海洋浮游病毒及其裂解浮游细菌释放的裂解产物的生态效应,本论文首先研究了西太平洋典型寡营养海区的浮游病毒对浮游细菌的致死效应;接着研究病毒裂解产物如何在不同营养水平(寡营养和富营养)特征的海洋水体中影响浮游细菌的生长、群落组成等生态特性。此外,本论文以海洋生态系统中一类生态地位非常重要的浮游细菌-玫瑰杆菌(Roseobacter)为研究对象,对其裂解性病毒进行了分离纯化和鉴定 ...
纪建达
core  

Detection of human cytomegalovirus cell‐free DNA in pregnant women with symptomatically infected fetuses: proof‐of‐concept study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 470-477, April 2025.
ABSTRACT Objective To evaluate the presence and levels of cytomegalovirus (CMV) cell‐free DNA (cfDNA) fragments in women pregnant with a fetus with symptomatic congenital CMV (cCMV). Methods The study comprised nine women whose fetuses were diagnosed with cCMV between June 2019 and July 2024 at 20 + 4 to 34 + 1 weeks' gestation (n = 8) or neonatally (n 
B. H. W. Faas   +9 more
wiley   +1 more source

高通量生物信息学分析对膀胱癌核心发病基因的预测及诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 探讨膀胱癌发病的关键基因以及发病机制通路。方法 通过GEO数据库搜索膀胱癌基因芯片测序结果,计算机R语言(limma数据包)对测序原始数据进行均一化处理,GEO2R检测差异基因,通过芯片融合分析锁定共同发病基因。使用最新版本生物信息学分析对膀胱癌测序结果进行数据挖掘,包括DAVID基因转换、基因本体分析、KEGG信号通路分析,STRING蛋白互作分析,Cytoscape可视化处理,cytohubba筛选膀胱癌关键基因。结果GSE61615包含2例膀胱癌组织和2例癌旁正常组织 ...
邢晨   +4 more
doaj  

The study of Mitochondrial DNA Gene Rearrangement in 4 species of birds(Aves: Falconiformes) [PDF]

open access: yes, 2016
线粒体控制区由于进化速率快,被作为分子标记广泛应用于种群遗传学和保护生物学等领域的研究。但最近在许多鸟类的线粒体中都发现控制区存在重复拷贝,并且2个控制区拷贝之间的碱基相似度较高。因此在扩增其中一个控制区基因时可能受到另一个控制区的干扰,而对研究结果产生影响。本研究主要针对隼形目鸟类线粒体DNA(mtDNA)基因组中控制区重复及由此产生的基因重排现象进行研究,初步探讨控制区重复和基因重排产生的过程和机制。 本次实验首次对鹰科中的白头鹞(Circusaeruginosus)、日本松雀鹰 ...
范欢
core  

Research on high-throughput detection of plasma cell-free DNA for targeted therapy-related genes screening and prognosis prediction in non-small cell lung cancer patients [PDF]

open access: yes
Background and purpose: High-throughput detection of plasma cell-free DNA (cfDNA) is widely used for multi-cancer targeted therapy drug screening, and this study investigated the relationship between the type and number of plasma cfDNA class Ⅰ and Ⅱ ...
DENG Qiling, SONG Di, XI Kexin, XIE Xiaoting, WU Xiaoyan, ZHAO Wei
core   +1 more source

Cloning and expreesion of three smad genes and two homologous genes of TGF-β in Trichinella spiralis [PDF]

open access: yes, 2015
旋毛虫是一种重要寄生虫,寄生于人、猪和鼠等多种动物体内产生致死性疾病。因旋毛虫病易感染,分布范围广泛和难治愈等特性,研究出能有效治疗旋毛虫病的制剂已成为全世界关注的热点。 哺乳动物中TGF-beta信号转导由TGF-β、Activin、inhibin、GDF、BMP和MIS等组成,TGF-beta参与细胞增殖分化、胚胎发育和骨形成的调控。在哺乳动物中TGF-beta信号途径的研究已经比较深入,但TGF-beta信号转导在旋毛虫中的报道还比较少。本文研究的smad-1和smad ...
刘燕
core  

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