Results 151 to 160 of about 329,291,499 (281)
Siracü'l-Kulub ve Eserdeki Hayvan Tespihleri
Sirâcü’l-Kulûb, Ahmed-i Dâ’î’ye atfedilen mensur bir eserdir. Eser, bir kısmı Hz. Peygambere, bir kısmı da Hz. Ali ve çeşitli sahabelere sorulan 70 meselenin cevaplandırılmasından ibarettir. Karşılaştırılan nüshalarda toplam 67 mesele görülmektedir. Bu meseleler arasında dikkati çeken hususlardan biri de hayvan tespihleridir.
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Hz. Peygamber Döneminde Müellefe-i Kulûb
In the battle of Hunayn, which occured during the period of Prophet Muhammad, substantial amount of booty was captured. Some part of the respective booty was given out to some people by Prophet Muhammad. Our research regarding those people called Muellefe-i Kulûb aims to identify them, and determine their impacts as a social class in the period of ...
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Ali Şir Nevayi`nin Mahbubu`l-Kulub ve Muhakimetü`l-Lugateyn adlı eserlerinde fiilimsiler
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Harputlu İshak Efendi ve Ziyâu`l-Kulûb adlı eseri
Osmanlı Devleti'nin son dönemlerinde; XIX. Yüzyılda misyonerlik faaliyetleri büyük bir artış göstermiştir. Osmanlı davleti siyasî yönden olduğu gibi, kültürel yönden de baskı altında kalmıştır. Osmanlı'nın ilk dönemlerinden beri Müslümanlar ile gayr-i müslimler hoşgörü içinde yaşamışlardır.
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