Results 61 to 70 of about 2,496,067 (290)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Projectes IX-X Ros 00-01 [PDF]

, 2001
"Aquesta publicació recull una selecció del treball produït, al llarg del curs 00-01, per un col·lectiu d'estudiants del darrer curs dins de l'assignatura de Projectes Arquitectònics, a l'Escola Tècnica Superior d'Arquitectura de Barcelona" -- Nota a l ...

core   +1 more source

Significance of suction/injection, gravity modulation, thermal radiation, and magnetohydrodynamic on dynamics of micropolar fluid subject to an inclined sheet via finite element approach

Case Studies in Thermal Engineering, 2021
This communication explores the significance of suction/injection for gravity modulation mixed convection in micropolar fluid flow due to an inclined sheet in the presence of magnetic field and thermal radiation.
Bagh Ali, Anum Shafiq, Imran Siddique, Qasem Al-Mdallal, Fahd Jarad   +4 more
doaj   +1 more source

Transverse phase space studies in TTF photoinjector during run 00-01: A comparison between simulation and experiment

, 2000
21 pp. (2000).
Piot, P., Flottmann, K., Schreiber, S., Sertore, D., Cianchi, A., Catani, L.   +5 more
openaire   +3 more sources

Trends in hospitalised injury, Australia: 1999-00 to 2010-11 [PDF]

, 2013
Summary This report describes trends in the occurrence of injuries requiring hospitalisation in Australia from 1 July 1999 to 30 June 2011. The annual number of cases rose from about 327,000 to 438,000 during this period.Injuries in 2010-11 Overall ...
Sophie Pointer
core  

Two‐Dimensional Triferroics: From Fundamental Couplings to Multifunctional Applications

Advanced Science, EarlyView.
This graphic summarizes the three main types of currently reported 2D triferroic couplings. From the structural perspective, existing systems can be broadly classified into two categories, which exhibit distinct symmetry features and coupling behaviors. Beyond the lattice difference, a third type involves the interplay among ferroelectricity, magnetism,
Yang Li, Jialin Gong, Zhiqing Li
wiley   +1 more source

Neurobehavioral side effects of corticosteroids during active treatment for acute lymphoblastic leukemia in children are age‐dependent: Report from Dana‐Farber Cancer Institute ALL Consortium Protocol 00‐01 [PDF]

Pediatric Blood & Cancer, 2011
AbstractBackgroundAlthough corticosteroids remain a mainstay of treatment for acute lymphoblastic leukemia (ALL), they can cause troublesome neurobehavioral changes during active treatment, especially in young children. We evaluated acute neurobehavioral side effects of corticosteroid therapy in preschool versus school‐age children by obtaining ...
Christine M, Mrakotsky, Lewis B, Silverman, Suzanne E, Dahlberg, M Cheryl A, Alyman, Stephen A, Sands, Jennifer T, Queally, Tamara P, Miller, Amy, Cranston, Donna S, Neuberg, Stephen E, Sallan, Deborah P, Waber   +10 more
openaire   +2 more sources

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

FX1498 npr-12(tm1498)IV | 2011-01-18T15:01:00+00:00

, 2017
<blockquote> <p>This experiment is part of the <em>C.elegans behavioural database</em>. For more information and the complete collection of experiments visit http://movement.openworm.org</p> </blockquote> <ul> ...
Javer, Avelino, Hokanson, Jim (5398172), Yemini, Eviatar (5398169), Grundy, Laura J, Hokanson, Jim, Kerr, Rex (5398163), Schafer, William R (5398166), Lee, Chee Wai (5398145), Brown, André EX (5398142), Ch'ng, Quee-Lim, Ch'ng, Quee-Lim (5398154), Currie, Michael (5398160), Brown, André EX, Javer, Avelino (5398151), Lee, Chee Wai, Li, Chris (5398175), Li, Kezhi, Kerr, Rex, Currie, Michael, Li, Chris, Li, Kezhi (5398157), Yemini, Eviatar, Schafer, William R, Grundy, Laura J (5398148)   +23 more
core   +1 more source

Near‐Unity Selectivity Inversion Between CO2 Electroreduction and H2 Evolution via Atomic Coordination Editing

Advanced Science, EarlyView.
Atomic coordination editing functions as an on/off switch that toggles single‐atom catalysts between CO2 electroreduction and hydrogen evolution. ABSTRACT Precise atomic coordination editing of single‐atom catalysts (SACs) provides an effective strategy to tune their electronic structures and catalytic selectivity. Yet, achieving near‐unity selectivity
Yukun Zhao, Yuanyuan He, Mengyu Duan, Peng Yin, Jinxing Chen, Xu Han, Jie Yang, Yulin Wang, Xingjie Fu, Shibo Xi, Chuncheng Chen, Jiong Lu   +11 more
wiley   +1 more source