Results 101 to 110 of about 1,721,024 (301)
Advanced Science, EarlyView.We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun +13 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
Machine learning techniques for real-time tillage quality assessment
The Indian Journal of Agricultural SciencesTillage quality significantly impacts soil structure, nutrient availability, and crop growth. The present study was carried out in 2024 in the delta region of Tamil Nadu at Puvalur village, Trichy District to evaluate tillage quality based on high ...
B PRIYADHARSHINI +5 more
doaj +1 more source
The role of language in engineering competence [PDF]
, 2005 The behaviour of engineered products is becoming less evident from their outward appearance. Thus many current engineered products have unseen properties that become evident only after protracted investigation, analysis or use.
Monk, John
core
Advanced Science, EarlyView.This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source
An outlook on mechanisms inciting drought tolerance in cotton (Gossypium hirsutum)
The Indian Journal of Agricultural SciencesDrought is a multifaceted abiotic stress that affects plants at morphological, physiological, biochemical, and molecular levels. In the face of increasing climate variability, plants exhibit diverse growth and reproductive responses to water scarcity ...
S MANJU +5 more
doaj +1 more source
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Advanced Science, EarlyView.Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
The Indian Journal of Agricultural SciencesThe experiment was conducted during rainy (kharif) seasons of 2023 and 2024 at Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu to study the application of nano DAP using a hybrid drone in groundnut (Arachis hypogaea L.) crops.
RAJESH P +5 more
doaj +1 more source
Hydra tropomyosin TROP1 is expressed in head-specific epithelial cells and is a major component of the cytoskeletal structure that anchors nematocytes [PDF]
, 1994 A cDNA clone encoding a 253 amino acid tropomyosin was isolated from Hydra in a differential screen for headspecific genes. The Hydra tropomyosin gene, designated trop1, is a single copy gene, lacks introns and is strongly expressed in tentacle-specific ...
Bosch, Thomas C. G. +3 more
core
Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics
Advanced Science, EarlyView.Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu +9 more
wiley +1 more source