Results 141 to 150 of about 259,122 (262)

Belzutifan efficacy in von Hippel-Lindau disease-associated renal cell carcinoma versus natural history control arm. [PDF]

J Natl Cancer Inst
Linehan WM, Jemielita T, Cornell J, Chen K, Ball MW, Srinivasan R, Liu Y, Perini RF, Pinto CA.   +8 more
europepmc   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

The long march towards testing the adenosine receptor agonism hypothesis for human cerebroprotection: The story of the A₁R/A₃R receptor agonist AST-004. [PDF]

Purinergic Signal
Liston TE, Korinek WS, Jacobson KA, Lechleiter JD.   +3 more
europepmc   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

DELETE 004

Ûridičnij časopis Nacìonalʹnoï akademìï vnutrìšnìh sprav, 2022
openaire   +1 more source

Compliance of Rural Water Quality to Global Target on SDG 6: Case Study of Osun State, Nigeria. [PDF]

Environ Health Insights
Ogunbode TO, Awolola VO, Owoeye OM, Atobatele BO, Akintunde EA, Akinola OT, Ayanbamiji OT.   +6 more
europepmc   +1 more source

Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor

Bulletin of the Korean Chemical Society, EarlyView.
This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim, Seongu Seong, Jung‐Ae Kim, Taeyeon Kwon, Hyun Jin Kim, Jeong‐Hoon Kim, Jong Yeon Hwang, Jin Hwa Cho, Kyoungmin Choi   +8 more
wiley   +1 more source

GOVT 110-004 Politics in the U.S.

, 2009
11 pages.Course syllabus for GOVT 110-004 Politics in the U.S. taught by Joumana Moukarim, American University, School of Public Affairs, Department of Government in Fall 2006.Submitted by Allison Feras (af4546a@american.edu) on 2009-10-01T21:42:14Z No ...

core  

Enterococcus faecalis KU-EF-004 enhances efficacy of anti-CTLA-4 immunotherapy for colorectal cancer via dendritic cell activation and gut microbiota modulation. [PDF]

BMC Immunol
Yamazaki T, Minami A, Kitagawa K, Yanase S, Ueki H, Shirakawa T.   +5 more
europepmc   +1 more source

The Synthesis Effects on the Performance of P2‐Na0.6Li0.27Mn0.73O2 Cathode Material for Sodium‐Ion Batteries

Battery Energy, Volume 4, Issue 2, March 2025.
The effect of reagents on the structure and performance of sodium‐layered oxides has not yet been thoroughly studied. This work explored this factor systematically through in situ high‐temperature XRD. The samples synthesized via MnCO3‐based precursors form the Li2MnO3 phase at evaluated temperature and perform better than those through MnO2‐based ...
Cuihong Zeng, Ziqin Zhang, Jiming Peng, Jia Qiao, Qichang Pan, Fenghua Zheng, Youguo Huang, Hongqiang Wang, Qingyu Li, Sijiang Hu   +9 more
wiley   +1 more source