Results 1 to 10 of about 233,983 (256)

A Comparison of the Antinociceptive Properties of SJP-005 and Morphine in Rats [PDF]

open access: yesPharmaceutics, 2021
SJP-005 (a combination of ketotifen and ibuprofen) is being developed as a potential treatment for pain and for opioid use disorder. It is therefore important to investigate the potential antinociceptive properties of SJP-005.
Joris C Verster   +3 more
doaj   +6 more sources

Characterization of ML-005, a Novel Metaproteomics-Derived Esterase [PDF]

open access: yesFrontiers in Microbiology, 2018
A novel gene encoding for a lipolytic enzyme, designated ML-005, was recently identified using a functional metaproteomics approach. We heterologously expressed this protein in Escherichia coli and biochemically characterized it.
Premankur Sukul   +2 more
doaj   +6 more sources

Identification of mRNAs related to endometrium function regulated by lncRNA CD36–005 in rat endometrial stromal cells

open access: yesReproductive Biology and Endocrinology, 2018
Background Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder in women of reproductive age and is commonly complicated by adverse endometrial outcomes.
Xueying Zhang   +8 more
doaj   +2 more sources

Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression [PDF]

open access: yesThe Journal of Headache and Pain
Background Migraine is a common neurovascular disorder that remains currently untreated in half of the patients. One third of migraine patients experience aura, which is associated with the development of cortical spreading depolarization (CSD), a wave ...
Flavia Brugia   +8 more
doaj   +2 more sources

The proline-rich antimicrobial peptide B7-005: low bacterial resistance, safe for human cells and effective in zebrafish embryo bacteraemia model [PDF]

open access: yesOpen Biology
Proline-rich antimicrobial peptides (PrAMPs) have gained attention due to their antimicrobial properties and low cytotoxicity. B7-005, a small optimized PrAMP, exhibits a broader spectrum of activity than native PrAMPs, due to an antimicrobial mechanism ...
Adriana Di Stasi   +12 more
doaj   +2 more sources

Extracellular biosynthesis of silver nanoparticle using Streptomyces sp. 09 PBT 005 and its antibacterial and cytotoxic properties [PDF]

open access: hybridApplied Nanoscience, 2014
The application of microorganisms for the synthesis of nanoparticles as an eco-friendly and promising approach is welcome due to its non-toxicity and simplicity. The aim of this study was to synthesize silver nanoparticle using Streptomyces sp.
Pachaiyappan Saravana Kumar   +5 more
openalex   +2 more sources

Assessment of genetically modified maize GA21 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐005) [PDF]

open access: diamondEFSA journal. European Food Safety Authority, 2017
Following the submission of application EFSA‐GMO‐RX‐005 under Regulation (EC) No 1829/2003 from Syngenta Crop Protection NV/SA, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a ...
Hanspeter Naegeli   +19 more
openalex   +2 more sources

Spectropolarimetry of PKS 0040-005 and the orientation of broad absorption line quasar [PDF]

open access: bronze, 2006
We have used the Very Large Telescope (VLT) to obtain spectropolarimetry of the radio-loud, double-lobed broad absorption line (BAL) quasar PKS 0040−005.
M. S. Brotherton   +2 more
openalex   +3 more sources

Effect of First-Line Serplulimab vs Placebo Added to Chemotherapy on Survival in Patients With Extensive-Stage Small Cell Lung Cancer: The ASTRUM-005 Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2022
Importance Programmed cell death ligand 1 inhibitors combined with chemotherapy has changed the approach to first-line treatment in patients with extensive-stage small cell lung cancer (SCLC). It remained unknown whether adding a programmed cell death 1 (
Ying Cheng   +24 more
semanticscholar   +1 more source

Potent dual MAGL/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain

open access: yesThe Journal of Headache and Pain, 2023
Background Engaging the endocannabinoid system through inhibition of monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), degrading endocannabinoids (endoCBs) 2-arachidonoylglycerol (2-AG) and anandamide (AEA), was proposed as a ...
Adriana Della Pietra   +9 more
semanticscholar   +1 more source

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