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PENERAPAN METODE STORY READING UNTUK MENINGKATKAN KEMAMPUAN BERBICARA ANAK USIA 5 - 6 TAHUN DI TK MELATI / ABA 005 PULAU BALAI [PDF]

Primary: Jurnal Pendidikan Guru Sekolah Dasar, 2015
This study aims to improve speaking skills of children aged 5-6 through methods Story Reading in TK Melati/ ABA 005 Pulau Balai. The method used is a Class Action Research. Class actions that researchers do the research is to use the method Story Reading
Hasnidar Hasnidar
doaj   +3 more sources

A Comparison of the Antinociceptive Properties of SJP-005 and Morphine in Rats

Pharmaceutics, 2021
SJP-005 (a combination of ketotifen and ibuprofen) is being developed as a potential treatment for pain and for opioid use disorder. It is therefore important to investigate the potential antinociceptive properties of SJP-005.
Joris C Verster, Andrew Scholey, Thomas A Dahl, Jacqueline M Iversen   +3 more
doaj   +2 more sources

Characterization of ML-005, a Novel Metaproteomics-Derived Esterase

Frontiers in Microbiology, 2018
A novel gene encoding for a lipolytic enzyme, designated ML-005, was recently identified using a functional metaproteomics approach. We heterologously expressed this protein in Escherichia coli and biochemically characterized it.
Premankur Sukul, Natalie Lupilov, Lars I. Leichert   +2 more
doaj   +2 more sources

Identification of mRNAs related to endometrium function regulated by lncRNA CD36–005 in rat endometrial stromal cells

Reproductive Biology and Endocrinology, 2018
Background Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder in women of reproductive age and is commonly complicated by adverse endometrial outcomes.
Xueying Zhang, Ying Xu, Lulu Fu, Dandan Li, Xiaowei Dai, Lianlian Liu, Jingshun Zhang, Lianwen Zheng, Manhua Cui   +8 more
doaj   +2 more sources

Circular RNA circLIMK1-005 promotes the progression of lung adenocarcinoma by interacting with RPA1 protein to activate CDK4 signaling [PDF]

Cell Death Discovery
Lung adenocarcinoma (LUAD) is the leading cause of cancer death worldwide. Circular RNAs (circRNAs) have emerged as potential key players in the onset and progression of various cancers.
Xia Yang, Lu Liu, Zhongjian Yu, Yuanlin Chen, Shiting Xu, Meiyuan Liu, Meng Wang, Huili Guo, Zhiwu Zhang, Bingjie Shan, Silin Cai, Mengting Pan, Jiangyu Zhang, Fengpin Wang, Yanfang Zheng   +14 more
doaj   +2 more sources

Effects of the Dual FAAH/MAGL Inhibitor AKU-005 on Trigeminal Hyperalgesia in Male Rats

Cells
The inhibition of endocannabinoid hydrolysis by enzymatic inhibitors may interfere with mechanisms underlying migraine-related pain. The dual FAAH/MAGL inhibitor AKU-005 shows potent inhibitory activity in vitro.
Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni, Sara Facchetti, Michela Palmisani, Valentina Franco, Cristina Tassorelli   +7 more
doaj   +2 more sources

Effect of First-Line Serplulimab vs Placebo Added to Chemotherapy on Survival in Patients With Extensive-Stage Small Cell Lung Cancer: The ASTRUM-005 Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance Programmed cell death ligand 1 inhibitors combined with chemotherapy has changed the approach to first-line treatment in patients with extensive-stage small cell lung cancer (SCLC). It remained unknown whether adding a programmed cell death 1 (
Ying Cheng, L. Han, Lin Wu, Jun Chen, Hongmei Sun, Guilan Wen, Yinghua Ji, M. Dvorkin, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, T. Melkadze, Yueyin Pan, Xuhong Min, M. Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Wen-ying Kang, Qingyu Wang, Jun Zhu   +24 more
semanticscholar   +1 more source

Antileukemic activity of YPN-005, a CDK7 inhibitor, inducing apoptosis through c-MYC and FLT3 suppression in acute myeloid leukemia

Heliyon, 2022
Acute myeloid leukemia (AML) is an aggressive blood cancer with a high rate of relapse associated with adverse survival outcomes, especially in elderly patients.
Bon-Kwan Koo, Eun-Ji Choi, Eun-Hye Hur, Ju Hyun Moon, Ji Yun Kim, Han-Seung Park, Yunsuk Choi, Jung-Hee Lee, Kyoo-Hyung Lee, Eun Kyung Choi, Jinhwan Kim, Je-Hwan Lee   +11 more
doaj   +1 more source

Potent dual MAGL/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain

The Journal of Headache and Pain, 2023
Background Engaging the endocannabinoid system through inhibition of monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), degrading endocannabinoids (endoCBs) 2-arachidonoylglycerol (2-AG) and anandamide (AEA), was proposed as a ...
Adriana Della Pietra, G. Krivoshein, Konstantin Ivanov, R. Giniatullina, H. Jyrkkänen, V. Leinonen, M. Lehtonen, A. M. van den Maagdenberg, Juha R. Savinainen, R. Giniatullin   +9 more
semanticscholar   +1 more source

Chitosan loaded RNA polymerase inhibitor nanoparticles increased attenuation in toxin release from Streptococcus pneumonia

Saudi Pharmaceutical Journal, 2023
Background: Multidrug-resistant (MDR) bacterial infections have become an emerging health concern around the world. Antibiotics resistance among S. pneumoniae strains increased recently contributing to increase in incidence of pneumococcal infection ...
Fulwah Yahya Alqahtani, Fadilah Sfouq Aleanizy, Hamad M. Alkahtani, Eram El Tahir, Siddique Akber Ansari, Atheer Alharbi, Asmaa Al-Bdrawy, Faiyaz Shakeel, Nazrul Haq, Lamees S. Al-Rasheed, Rihaf Alfaraj, Abdullah K. Alshememry, Ibrahim A. Alsarra   +12 more
doaj   +1 more source