Results 121 to 130 of about 1,566,936 (371)

q.07, Image 005

, 2023
:unav
openalex   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Analysis of CLAS data on double charge pion electroproduction

, 2007
Recent developments in phenomenological analysis of the CLAS data on 2$\pi$ electroproduction are presented. The contributions from isobar channels and $P_{11}(1440)$, $D_{13}(1520)$ electrocouplings at $Q^{2}$ from 0.25 to 0.6 GeV$^2$ were determined ...
A. Kiswandhi, A. Matsuyama, G.V. Fedotov, I.G. Aznauryan, I.G. Aznauryan, J.C. Nacher, M. Ripani, V. Mokeev, V. Mokeev, V. Mokeev, V.D. Burkert, V.I. Mokeev, V.I. Mokeev   +12 more
core   +1 more source

Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases

Advanced Science, EarlyView.
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim, Arshad J. Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B. Katz, Yong Zhang   +8 more
wiley   +1 more source

Branching Fractions and CP Asymmetries of B→K0*1430ρω and B→K0*1430ϕ Decays in the Family Nonuniversal Z′ Model

Advances in High Energy Physics, 2013
Within the QCD factorization framework, we investigate the branching fractions and the direct CP asymmetries of decays B→K0*1430ρω and B→K0*1430ϕ under two different scenarios in the standard model and the family nonuniversal Z′ model.
Ying Li, En-Lei Wang, Hong-Yan Zhang
doaj   +1 more source

RADA16 and SAAP148 Peptide‐Modified Collagen Self‐Assembled Hydrogels for Accelerated Healing of Infected Wounds

Advanced Science, EarlyView.
Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu, Jiawei Wu, Ho‐Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen, Xin Zhao, Zhuoyue Chen   +8 more
wiley   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

LB-005 Post-infection Dysbiosis – A Potential Cause Of Irritable Bowel Syndrome? [PDF]

, 2014
Meghan Acres, S. Michele Owen, Rachael J. Rigby   +2 more
openalex   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

Tunable Charge Transport Properties Through Precise π‐Stacking Modulation in Isostructural Porous Molecular Conductors

Angewandte Chemie, EarlyView.
An intrinsic structure–property relationship in through‐space conductive MOFs is investigated using a series of counterion‐free porous molecular conductors (PMC‐3) with carrier‐doped π‐stacked columns. The constant carrier density and halide‐dependent tunable π‐stacking geometry in PMC‐3 enable the discovery of a linear correlation between the lattice ...
Liyuan Qu, Hiroaki Iguchi, Kenta Ueno, Shinya Takaishi, Masahiro Yamashita, Chanel F. Leong, Deanna M. D'Alessandro, Takao Tsumuraya, Wakana Matsuda, Shu Seki, Ryotaro Matsuda   +10 more
wiley   +2 more sources