Results 121 to 130 of about 1,486,473 (398)

WTAP Mediated m6A Modification Stabilizes PDIA3P1 and Promotes Tumor Progression Driven by Histone Lactylation in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang   +13 more
wiley   +1 more source

Entropy Maximization, Cutoff Distribution, and Finite Stellar Masses

open access: yesAdvances in Astronomy, 2008
Conventional equilibrium statistical mechanics of open gravitational systems is known to be problematical. We first recall that spherical stars/galaxies acquire unbounded radii, become infinitely massive, and evaporate away continuously if one uses the ...
Ritesh Kumar Dubey   +3 more
doaj   +1 more source

DNA alterations in blood cells of Channa punctatus after acute exposure to 4-Nonylphenol

open access: yesIndian Journal of Animal Sciences, 2020
The DNA damaging effect of 4-nonylphenol was evaluated in blood cells of fish Channa punctatus by using single gel electrophoresis assay (SGEA). Fish were exposed to three sublethal concentrations (0.15 mg/l, 0.31 mg/l and 0.63 mg/l) of 4-NP which were ...
MADHU SHARMA   +2 more
doaj   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He   +11 more
wiley   +1 more source

A European perspective on intravascular catheter-related infections: report on the microbiology workload, aetiology and antimicrobial susceptibility (ESGNI-005 Study).

open access: yesClinical Microbiology and Infection, 2004
The laboratory workload, microbiological techniques and aetiology of catheter-related infections in European hospitals are mostly unknown. The present study (ESGNI-005) comprised a 1-day (22 October 2001), laboratory-based, point-prevalence survey based ...
E. Bouza   +5 more
semanticscholar   +1 more source

Crystallization Mechanism of Hard Sphere Glasses [PDF]

open access: yes, 2011
In supercooled liquids, vitrification generally suppresses crystallization. Yet some glasses can still crystallize despite the arrest of diffusive motion.
Chantal Valeriani   +8 more
core   +2 more sources

Natural Dextran as an Efficient Interfacial Passivator for ZnO‐Based Electron‐Transport Layers in Inverted Organic Solar Cells

open access: yesAdvanced Energy Materials, EarlyView.
A natural dextran is introduced as an efficient interfacial modifier for the ZnO‐based electron transport layer (ETL) in inverted organic solar cells (OSCs). This modification effectively passivates defects in the ZnO layer and reduces interfacial charge carrier recombination, enabling the achievement of high efficiency, enhanced stability, and broad ...
Bin Zhang   +10 more
wiley   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

open access: yesAggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail   +5 more
wiley   +1 more source

q-Deformed Kink Solutions

open access: yes, 2006
The q-deformed kink of the $\lambda\phi^4-$model is obtained via the normalisable ground state eigenfunction of a fluctuation operator associated with the q-deformed hyperbolic functions.
A. F. DE LIMA   +5 more
core   +1 more source

Addition of a dairy fraction rich in milk fat globule membrane to a high-saturated fat meal reduces the postprandial insulinaemic and inflammatory response in overweight and obese adults. [PDF]

open access: yes, 2016
Meals high in SFA, particularly palmitate, are associated with postprandial inflammation and insulin resistance. Milk fat globule membrane (MFGM) has anti-inflammatory properties that may attenuate the negative effects of SFA-rich meals.
Demmer, Elieke   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy