Results 171 to 180 of about 1,566,936 (371)

Monetary and exchange rate policy in Austria: an early example of policy coordination [PDF]

open access: yes
This paper describes the evolution of Austrian exchange rate and monetary policy as an example of the benefits of policy coordination and credibility. This policy proved the performance of the Central Bank in achieving its twin objective of stabilizing ...
Dieter Proske   +2 more
core  

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens   +10 more
wiley   +1 more source

Patent policy, patent pools, and the accumulation of claims in sequential innovation [PDF]

open access: yes
We present a dynamic model where the accumulation of patents generates an increasing number of claims on sequential innovation. We study the equilibrium innovation activity under three regimes: patents, no-patents and patent pools.
Gaston Llanes, Stefano Trento
core  

Preoperative Detection of Dual TERT Promoter Mutations in Thyroid Cancer: A Case Series

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Telomerase reverse transcriptase promoter (TERTp) mutations are associated with aggressive thyroid cancer and are most frequently found in anaplastic and poorly differentiated thyroid cancer. Pre‐operative thyroid nodule molecular testing can detect TERTp, denoting a high risk of malignancy and possible aggressive clinical features such as ...
Amir Harari   +7 more
wiley   +1 more source

Aggregate price shocks and financial instability: a historical analysis [PDF]

open access: yes
This paper presents empirical evidence on the hypothesis that aggregate price disturbances cause or worsen financial distress. We construct two annual indexes of financial conditions for the United States covering 1790-1997, and estimate the effect of ...
David C. Wheelock   +2 more
core  

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma   +5 more
wiley   +1 more source

ANALYSIS OF ECONOMIC GAPS BETWEEN URBAN AND RURAL ROMANIAN AREAS [PDF]

open access: yes
In this paper the authors will perform a comparative analysis of the impact that the population residential areas have on the economic and social activity from Romania.
Gîdiu Valeria, Toader Valentin
core  

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore   +7 more
wiley   +1 more source

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