Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
ABSTRACT Parabens (parahydroxybenzoates), which are frequently used as preservatives in pharmaceuticals, foodstuffs, and personal care products, have recently attracted considerable attention due to their adverse health effects and endocrine‐disrupting properties.
Jung‐Wei Chang +5 more
wiley +1 more source
Metagenome-assembled genome sequence of <i>Candidatus</i> Loosdrechtia sp. KJ reconstructed from an alkaline anammox reactor. [PDF]
Chuang H-Y +4 more
europepmc +1 more source
Non‐Uniform Programmable Photonic Waveguide Meshes
Integrating defect cells into uniform hexagonal waveguide meshes overcomes the fundamental spectral and temporal limitations of programmable photonics. By leveraging the Vernier effect through non‐uniform coupled cavities, this architecture achieves a tenfold increase in free spectral range and ultra‐fast sampling times, paving the way for next ...
Cristina Catalá‐Lahoz, José Capmany
wiley +1 more source
Executive function mediates prefrontal excitation-inhibition balance and emotion recognition in euthymic bipolar disorder. [PDF]
Wu CY +10 more
europepmc +1 more source
Liking Without Endorsing: Consumer Dilemmas in Responses to AI‐Generated Music
ABSTRACT Despite a growing literature documenting consumer aversion to AI‐generated creative output, AI‐generated music has achieved notable success in the marketplace, with some songs achieving chart placements and attracting millions of streams.
Andrew B. Edelblum, Joshua Poe
wiley +1 more source
Investigation of miRNAs affecting schwann cells in patients with trigeminal neuralgia. [PDF]
Onrat ST +4 more
europepmc +1 more source
Leveraging Public Transit for Robotic Deliveries: A Column Generation Approach
ABSTRACT Autonomous mobile robots (AMRs) are small, electric, wheeled vehicles that operate at pedestrian speeds. In the last‐mile delivery service considered in this study, a fleet of AMRs is deployed across multiple recharging depots within a service area, from which they depart to perform point‐to‐point deliveries. We consider an operational setting
Yishay Shapira, Mor Kaspi
wiley +1 more source
Thrombomodulin facilitates melanoma progression via FAK- and ezrin-mediated phenotypic plasticity. [PDF]
Kuo CH +6 more
europepmc +1 more source
Accurate functional trait data are essential for understanding ecosystem services and processes in fragmented landscapes. We evaluated whether the global EltonTraits 1.0 database adequately represents the functional structure of mammal communities in forest fragments and restoration sites in a highly fragmented Atlantic Forest landscape.
Maria F. R. Godoi +5 more
wiley +1 more source

