Results 261 to 270 of about 455,273 (283)

Aromatic Organic Small-Molecule Material with (020) Crystal Plane Activation for Wide-Temperature and 68000 Cycle Aqueous Calcium-Ion Batteries.

ACS Nano, 2023
Calcium-ion batteries are an emerging energy storage device owing to the low redox potential of Ca2+/Ca and the naturally abundant reserves of the Ca element.
Fan Qiao, Jun-Jun Wang, Ruohan Yu, Meng Huang, Lei Zhang, Wei Yang, Hong Wang, Jin-Song Wu, Lei Zhang, Yalong Jiang, Q. An   +10 more
semanticscholar   +1 more source

Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design.

Journal of Medicinal Chemistry, 2021
This publication details the successful use of FBDD (fragment-based drug discovery) principles in the invention of a novel covalent Bruton's tyrosine kinase inhibitor, which ultimately became the Takeda Pharmaceuticals clinical candidate TAK-020 ...
Mark Sabat, D. Dougan, B. Knight, J. Lawson, N. Scorah, Christopher R. Smith, E. Taylor, P. Vũ, C. Wyrick, Haixia Wang, Deepika Balakrishna, M. Hixon, L. Madakamutil, Donavon J. McConn   +13 more
semanticscholar   +1 more source

b-axis phase boundary movement induced (020) plane cracking in LiFePO4.

ACS Applied Materials and Interfaces, 2020
Phase boundary movement accomplishing reversible LiFePO4/FePO4 biphasic transition is a fundamental Li ion intercalation/deintercalation mechanism for LiFePO4 cathode. Phase boundary energetically favors crack nucleation and propagation, thus, postmortem
Junjie Fu, Kuan Wang, Dan-Min Liu, Zhenlu Zhang, Man-Ling Sui, P. Yan   +5 more
semanticscholar   +1 more source

Alleviation of brain injury by applying TGN-020 in the supraoptic nucleus via inhibiting vasopressin neurons in rats of focal ischemic stroke.

Life Science, 2020
AIMS To understand mechanisms underlying vasopressin hypersecretion in stroke and its association with brain injury, we investigated effects of blocking aquaporin 4 (AQP4) in the supraoptic nucleus (SON) on vasopressin neuronal activity and cerebral ...
D. Cui, Shu-Wei Jia, Tong Li, Dongyang Li, Xiao-Ran Wang, Xiao-Yu Liu, Yu-Feng Wang   +6 more
semanticscholar   +1 more source

Batch and fixed-bed adsorption behavior of porous boehmite with high percentage of exposed (020) facets and surface area towards Congo red

, 2020
Boehmite adsorbents with high percentage of exposed (020) facets and large specific surface area were prepared by a separate nucleation and aging steps route with excellent performance towards Congo red in batch and fixed-bed adsorption columns.
Zijia Li, Li He, W. Tian, Ren-Yao Huang, Xingpeng Wang, Dian-Qing Li, Ping-Gui Tang, Yong-Jun Feng   +7 more
semanticscholar   +1 more source

Highly self-oriented growth of (020) and (002) monoclinic HfO2 thick films using laser chemical vapor deposition

, 2020
Monoclinic hafnia (m-HfO2) films were prepared on polycrystalline AlN substrates via thermal and laser chemical vapor deposition (thermal CVD and laser CVD).
S. Matsumoto, Y. Kaneda, Akihiko Ito
semanticscholar   +1 more source

TGN‐020 alleviates edema and inhibits astrocyte activation and glial scar formation after spinal cord compression injury in rats

Life Science, 2019
Aims: Identifying drugs that inhibit edema and glial scar formation and increase neuronal survival is crucial to improving outcomes after spinal cord injury (SCI).
Jian Li, Zhiqiang Jia, Wen Xu, Weidong Guo, Mingchao Zhang, J. Bi, Yang Cao, Zhong-Kai Fan, Gang Li   +8 more
semanticscholar   +1 more source

New Antibacterial Peptaibiotics against Plant and Fish Pathogens from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020.

Journal of Agricultural and Food Chemistry
Bacterial diseases could severely harm agricultural production. To develop new antibacterial agents, the secondary metabolites of a deep-sea-derived fungus Simplicillium obclavatum EIODSF 020 with antibacterial activities against plant and fish pathogens
Xiao Liang, Jia-Fan Yang, Zhong-Hui Huang, Xuan Ma, Yan Yan, Shu-Hua Qi   +5 more
semanticscholar   +1 more source

Proposed rituximab biosimilar BCD‐020 versus reference rituximab for treatment of patients with indolent non‐Hodgkin lymphomas: An international multicenter randomized trial

Hematological Oncology, 2019
BCD‐020 is a proposed rituximab biosimilar, which has shown high similarity to rituximab in quality and nonclinical studies in vitro and in vivo.
I. Poddubnaya, S. Alekseev, K. Kaplanov, L. Lukavetskyy, G. Rekhtman, T. Dolai, V. Attili, C. Bermúdez, A. Isaev, E. Chernyaeva, R. Ivanov   +10 more
semanticscholar   +1 more source