Results 361 to 370 of about 682,890 (403)

Final analysis of the CheckMate 025 trial comparing nivolumab (NIVO) versus everolimus (EVE) with >5 years of follow-up in patients with advanced renal cell carcinoma (aRCC).

, 2020
617Background: CheckMate 025 demonstrated superior overall survival (OS) in previously treated patients (pts) with aRCC, with improved safety and tolerability in the NIVO arm compared with EVE.
R. Motzer, S. Tykodi, B. Escudier, S. Oudard, H. Hammers, D. McDermott, S. George, D. Castellano, T. Choueiri, A. Alva, M. Richardet, E. Plimack, S. Srinivas, G. Procopio, F. Donskov, H. Gurney, Y. Tomita, M. McHenry, S. S. Saggi, N. Tannir   +19 more
semanticscholar   +1 more source

Evaluation of predictive biomarkers for nivolumab in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) from the CheckMate-025 (CM-025) trial.

Journal of Clinical Oncology, 2020
5023 Background: We previously showed that levels of CD8+ tumor infiltrating cells (TIC) expressing PD-1 but not TIM-3 and LAG-3 (CD8+ PD1+TIM3−LAG3−) were associated with response to nivolumab (nivo) in pretreated mccRCC pts (Pignon et al, 2019).
M. Ficial, O. Jegede, M. Sant'angelo, S. Moreno, D. Braun, M. Wind-Rotolo, Jean-Christophe Pignon, P. Catalano, Maxine Sun, E. Allen, G. Freeman, A. Sharpe, F. Hodi, R. Motzer, Catherine J. Wu, M. Atkins, D. McDermott, S. Shukla, T. Choueiri, S. Signoretti   +19 more
semanticscholar   +1 more source

025 Management and outcomes of febrile infants [PDF]

Emergency Medicine Journal, 2011
Objectives and BackgroundOne of the new Emergency Department (ED) clinical quality indicators (CQIs) defines febrile infants as “high risk” patients requiring consultant “sign-off” prior to discharge. A service evaluation of the management and outcomes of febrile infants attending our ED in 2010 was undertaken in order to determine how our department ...
M Hare, D Burke, C Rimmer
openaire   +1 more source

Nivolumab versus everolimus in advanced renal cell carcinoma: Japanese subgroup 3-year follow-up analysis from the Phase III CheckMate 025 study.

Japanese Journal of Clinical Oncology, 2019
BACKGROUND Nivolumab treatment resulted in superior efficacy and safety versus everolimus treatment in the 2-year follow-up of the CheckMate 025 Phase III study, with consistent results in the global population and the Japanese population.
Y. Tomita, S. Fukasawa, N. Shinohara, H. Kitamura, M. Oya, M. Eto, K. Tanabe, M. Saito*, G. Kimura, J. Yonese, M. Yao, H. Uemura   +11 more
semanticscholar   +1 more source

025 Guest Lecture

Journal of Neurology, Neurosurgery & Psychiatry, 2010
Abstract: It is well recognised that diseases of the peripheral nervous system can be caused by autoantibodies and respond well to immunotherapies associated with a fall in antibody levels. The best examples are, of course, myasthenia gravis and the Lambert Eaton myasthenic syndrome with antibodies to the acetylcholine receptor and voltage gated ...
openaire   +2 more sources

1-025-MixingItUp-ModelingScenario

2022
Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.
openaire   +1 more source

DI-025 Intravenous immunoglobulin induced agranulocytosis [PDF]

Drug information and pharmacotherapy, 2017
Background Leukoneutropenia is described in most of the summaries of the characteristics of the products of human intravenous immunoglobulins (ivIg). This side effect is uncommon and not usually described in paediatric populations. Since 1998, less than 200 cases have been reported in the literature.
L Decarout, M Hermet, M Zenut
openaire   +1 more source

PS-025 Quality metrics for hygiene monitoring [PDF]

Patient safety and risk management, 2015
Background Aseptic production is performed by approximately 100 operators. According to the Quality Management System, sampling is performed daily on all operators, both hands. The acceptance criteria established is, that on the total of two gloves; one viable microorganism is accepted.
K Johnsen, D Hvid
openaire   +1 more source

Complication and safety of ultrasound guided percutaneous nephrolithotomy in 8 025 cases in China

Chinese Medical Journal, 2014
Background Percutaneous nephrolithotomy (PCNL) was mostly performed with fluoroscopy and/or ultrasonography. The safety and feasibility of PCNL performed totally under ultrasound are not clearly defined. Therefore, we introduce the 9‐year experience of 8
Jianxing Li, Bo Xiao, Wei-guo Hu, Bo Yang, Liang Chen, Hao Hu, Xiaofeng Wang   +6 more
semanticscholar   +1 more source

DI-025 Valganciclovir in liver transplanted patients

Drug information and pharmacotherapy, 2016
Background Cytomegalovirus (CMV) infection is the most common viral infection after solid organ transplantation, and is an important cause of mortality and morbidity in this group of patients. Valganciclovir is used to treat and prevent this condition.
A De Leon, T Betancor, J Merino, A Montero, Esteve Fernández, I Plasencia   +5 more
openaire   +2 more sources