Results 71 to 80 of about 1,095,002 (314)

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister   +14 more
wiley   +1 more source

Caffeic acid functionalized silver nanoparticles: A bionanoformulation and its assessment of cell cycle and in vitro cytotoxicity

open access: yesNext Nanotechnology
Caffeic acid, a potent polyphenol belonging to the hydroxycinnamic acid derivative class, was utilized in the synthesis of silver nanoparticles (AgNPs) at ambient temperature.
Sangeetha Pushpanathan   +5 more
doaj   +1 more source

Crystal structure of 2-{[(naphthalen-1-yl)oxy]methyl}-5-(2,4,5-trifluorophenyl)-1,3,4-oxadiazole

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound C19H11F3N2O2, the oxadiazole ring and the naphthalene ring system are approximately planar (r.m.s. deviations of 0.001 and 0.020 Å, respectively) and the oxadiazole ring makes dihedral angles of 13.11 (1) and 7.59 (1)° with the ...
Muniyappan Govindhan   +3 more
doaj   +1 more source

Solo singing [PDF]

open access: yes, 2017
Робоча програма з дисципліни "Сольний спів" IІІ курс для студентів галузі 025 Музичне мистецтво (Сольний спів), перший бакалаврський освітній рівень.Программа работы по дисциплине «Сольное пение» IІІ курс для студентов отделения 025-Музыкальное искусство,
Тетеря, Віктор Михайлович
core  

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

Ансамблевый класс [PDF]

open access: yes, 2017
Робоча програма навчальної дисципліни «Ансамблевий клас» для студентів 5 курсу за спеціальністю 025 «Музичне мистецтво» (Сольний спів) другого(«магістерського») освітнього рівня.Рабочая программа учебной дисциплины «Ансамблевый класс» для студентов 5 ...
Ланіна, Тетяна Олександрівна
core   +2 more sources

Crystal structure of 2-(4-fluoro-3-methylphenyl)-5-{[(naphthalen-1-yl)oxy]methyl}-1,3,4-oxadiazole

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C20H15FN2O2, adopts an almost planar conformation. The oxadiazole ring makes dihedral angles of 13.90 (1) and 7.93 (1)° with the naphthalene ring system and benzene ring, respectively, while the naphthalene ring system and benzene ...
Muniyappan Govindhan   +3 more
doaj   +1 more source

Рабочая программа учебной дисциплины Сольное пение [PDF]

open access: yes, 2017
Робоча програма навчальної дисципліни «Сольний спів» для студентів 2 курсу за спеціальністю 025 «Музичне мистецтво» (Сольний спів) першого («бакалаврського») освітнього рівня.Work program of the discipline "Solo singing" for students of the second year ...
Гмиріна, Світлана Вікторівна
core  

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

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