Synthesis and Anticancer Activity of Some New S-Glycosyl and S-Alkyl 1,2,4-Triazinone Derivatives [PDF]
Molecules, 2011 A series of S-glycosyl and S-alkyl derivatives of 4-amino-3-mercapto-6-(2-(2-thienyl)vinyl)-1,2,4-triazin-5(4H)-one (1) were synthesized using different halo compounds such as preacetylated sugar bromide, 4-bromobutylacetate, 2-acetoxyethoxy-methyl ...
Hosam A. Saad, Ahmed H. Moustafa
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New Heterocyclic Compounds from Oxazol-5(4H)-one and 1,2,4-Triazin-6(5H)-one Classes: Synthesis, Characterization and Toxicity Evaluation [PDF]
Molecules, 2023 This paper describes the synthesis of new heterocycles from oxazol-5(4H)-one and 1,2,4-triazin-6(5H)-one classes containing a phenyl-/4-bromophenylsulfonylphenyl moiety.
Stefania-Felicia Barbuceanu +12 more
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Fluorine Substituted 1,2,4-Triazinones as Potential Anti-HIV-1 and CDK2 Inhibitors [PDF]
Journal of Chemistry, 2014 Fluorine substituted 1,2,4-triazinones have been synthesized via alkylation, amination, and/or oxidation of 6-(2-amino-5-fluorophenyl)-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one 1 and 4-fluoro-N-(4-fluoro-2-(5-oxo-3-thioxo-2,3,4,5-tetrahydro-1,2,4 ...
Mohammed S. I. Makki +2 more
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Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis. [PDF]
Molecules, 2023 This review uses the National Cancer Institute (NCI) COMPARE program to establish an extensive list of heterocyclic iminoquinones and quinones with similarities in differential growth inhibition patterns across the 60-cell line panel of the NCI ...
Haji N +4 more
europepmc +3 more sources
Eco-friendly plant growth and development regulators on the basis of derivatives 1,2,4-triazines [PDF]
BIO Web of Conferences, 2021 The article considers the application of plant growth and development regulators, in particular, derivatives of asymmetric triazines. A method for obtaining hexahydro-1,2,4-triazinone-3 is given.
Builova E.A. +4 more
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Production of PVC-films with specific properties [PDF]
Нанотехнологии в строительстве, 2018 When developing polymeric materials with specified properties special compounds such as fungicides are used alongside traditional chemical additives (plasticizers).
MASKOVA Albina Rafitovna +4 more
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Synthesis, Characterization, and Biological Evaluation of Novel 7-Oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic Acid Derivatives [PDF]
Molecules, 2020 A series of novel 7-oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic acid derivatives was synthesized in good yields by a multi-step procedure that included the generation of the S-alkylated derivatives from 6-substituted arylmethyl-3-mercapto-1,2,4 ...
Dong Cai +7 more
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Reversible Modulation of Motile Cilia by a Benzo[e][1,2,4]triazinone: A Potential Non-Hormonal Approach to Male Contraception [PDF]
CellsMotile cilia play essential roles in various physiological processes including fluid flow generation and sperm motility. In this study, we identified 1,3-diphenyl-6-(4-phenylpiperazin-1-yl)benzo[e][1,2,4]triazin-7(1H)-one as a potent and reversible ...
Maria Chatzifrangkeskou +6 more
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Design, synthesis and antibacterial activity of novel 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives [PDF]
HeliyonBased on the observed biological activity of 1,2,4-triazin-5-one derivatives and their cyclic analogues, a novel series of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives that contain ester moiety compounds 3a-3g, carboxylic acid moiety compounds 4a ...
Shicheng Hou +9 more
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Development of PVC films, resistant mold influence [PDF]
E3S Web of Conferences, 2019 Along with the use of plasticizers in the development of polymeric materials with specific properties, special substances such as fungicides are also used because of the negative impact on the polyvinyl chloride materials of microorganisms.
Mazitova Aliya +2 more
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