Results 1 to 10 of about 305 (99)

Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling [PDF]

, 2013
Exposure of animals to perfluorooctanoic acid (PFOA), a surfactant used in emulsion polymerization processes causes early pregnancy loss, delayed growth and development of fetuses. The mechanisms of action are largely unknown.
Chai, J, Cheung, TY, Kodithuwakku, SPK, Lee, CKF, Tsang, H, Wong, CK, Yeung, WSB   +6 more
core   +1 more source

Regulation of hepatic level of fatty-acid-binding protein by hormones and clofibric acid in the rat [PDF]

, 1994
Regulation of the hepatic level of fatty-acid-binding protein (FABP) by hormones and p-chlorophenoxyisobutyric acid (clofibric acid) was studied. The hepatic level of FABP, measured as the oleic acid-binding capacity of the cytosolic FABP fraction, was ...
S Nakagawa, Y Kawashima, A Hirose, H Kozuka   +3 more
core   +1 more source

Lipidomics Reveals Reduced Inflammatory Lipid Species and Storage Lipids after Switching from EFV/FTC/TDF to RPV/FTC/TDF: A Randomized Open-Label Trial [PDF]

, 2020
HIV and antiretroviral therapy affect lipid metabolism. Lipidomics quantifies several individual species that are overlooked using conventional biochemical analyses, outperforming traditional risk equations.
Burgos, J., CRESPO CASAL, MANUEL, Curran, A., Falc?, V., Martin-Castillo, M., Navarro, J., Peraire, J., Planas, B., Ribera, E., Rull, A., Torrella, A., Vidal-Gonz?lez, J.   +11 more
core   +1 more source

Peroxisomes proliferation and pharmacological stimulation of autophagy in rat liver: evidence to support that autophagy may remove the “older” peroxisomes [PDF]

, 2017
Like mitochondria, peroxisomes produce reactive oxygen species (ROS), compounds which have been implicated to play an important role in many degenerative diseases and aging itself, and an exaggerated ROS production might occur in altered or older ...
Bergamini, Ettore, Cavallini, Gabriella, Donati, Alessio, Taddei, Michele   +3 more
core   +1 more source

Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression

Journal of Extracellular Vesicles, Volume 7, Issue 1, December 2018., 2018
ABSTRACT Urine contains extracellular vesicles (EVs) that concentrate molecules and protect them from degradation. Thus, isolation and characterisation of urinary EVs could increase the efficiency of biomarker discovery. We have previously identified proteins and RNAs with differential abundance in urinary EVs from prostate cancer (PCa) patients ...
Marc Clos‐Garcia, Ana Loizaga‐Iriarte, Patricia Zuñiga‐Garcia, Pilar Sánchez‐Mosquera, Ana Rosa Cortazar, Esperanza González, Verónica Torrano, Cristina Alonso, Miriam Pérez‐Cormenzana, Aitziber Ugalde‐Olano, Isabel Lacasa‐Viscasillas, Azucena Castro, Felix Royo, Miguel Unda, Arkaitz Carracedo, Juan M. Falcón‐Pérez   +15 more
wiley   +1 more source

The gene expression profiles of canine mammary cancer cells grown with carcinoma-associated fibroblasts (CAFs) as a co-culture in vitro [PDF]

, 2012
Background It is supposed that fibroblasts present in tumour microenvironment increase cancer invasiveness and its ability to metastasize but the mechanisms have not been clearly defined yet. Thus, the current study was designed to assess changes in gene
Dolka, Izabella, Jank, Michał, Król, Magdalena, Maciejewski, Henryk, Manuali, Elisabetta, Motyl, Tomasz, Pawłowski, Karol M, Szyszko, Katarzyna   +7 more
core   +3 more sources

Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord [PDF]

, 2018
To obtain a thorough understanding of chronic pain, large-scale molecular mapping of the pain axis at the protein level is necessary, but has not yet been achieved. We applied quantitative proteome profiling to build a comprehensive protein compendium of
Allison M. Barry, David Gomez-Varela, Jan-Hendrik Sondermann, Julia R. Sondermann, Manuela Schmidt   +4 more
core   +10 more sources

Comparative toxicometabolomics of perfluorooctanoic acid (PFOA) and next-generation perfluoroalkyl substances [PDF]

, 2020
) was significantly correlated with alkyl chain-length, and toxic concentrations were quantitatively similar to those reported previously for PFAS. Metabolic profiling of zebrafish embryos exposed to selected PFAS, specifically including PFOA and two ...
Alia, A., Bai, T., Berry, J.P., Eeza, M.N.H., Gebreab, K.Y., Matysik, J., O'Shea, K.E., Zuberi, Z.   +7 more
core   +2 more sources

Biophysical properties of aqueous humour in ocular pathologies [PDF]

, 2016
El limbo corneoescleral contiene estructuras diseñadas para evacuar el humor acuso desde la cámara anterior del ojo hacia la circulación general. Estos elementos se encuentran entre el espolón escleral y la línea de Schwalbe que finalmente se continua ...
Cabrerizo Núñez, Francisco Javier
core   +3 more sources

Fatty acid modification of cells in culture by overexpression of exogenous desaturases [PDF]

, 1999
COS-1 cells were transfected transiently with expression vectors encoding stearoyl-acyl-carrier-protein desaturase (SACPD) from castor bean, stearoyl-CoA desaturase (SCD) from mice, and a control vector containing SACPD cDNA in reverse orientation.
Knight, Travis Jay
core   +2 more sources