Results 111 to 120 of about 1,584,796 (357)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A Note on the Sri Lankan Experience in Poverty Reduction [PDF]

open access: yes
‘Poverty’ is a complex, multifaceted and much investigated subject which has generated an colossal amount of literature. The situation in relation to Sri Lanka is no different—both in relation to the complexity of the subject and the investigation and ...
Neranjana Gunetilleke
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Does more for the poor mean less for the poor? The politics of tagging [PDF]

open access: yes
Proposals aimed at improving the welfare of the poor often include indicator targeting, in which non-income characteristics (such as race, gender, or land ownership) that are correlated with income are used to target limited funds to groups likely to ...
Gelbach, Jonah B., Pritchett, Lant H.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Sengkarut kemiskinan masyarakat desa dalam novel Aib dan Nasib karya Minanto

open access: yesDiglosia
This research was carried out with the aim of analyzing (1) the structure of “Aib dan Nasib” with heuristic reding, (2) the village and its chaos in poverty according to Robert Chambers' view, and (3) the reasons why the village community experiences a ...
Chintya Angesty   +2 more
doaj   +1 more source

Nudging Charitable Giving: The ethics of Nudge in international poverty reduction

open access: yesEthics & Global Politics, 2017
The use of nudge theory by non-governmental organizations and governments as a means to encourage charitable donations in order to address global poverty has been the subject of much recent enthusiasm.
Joshua Hobbs
doaj   +1 more source

Trends in Financial Poverty in OECD Countries

open access: yes, 1996
This paper investigates trends in financial poverty in OECD countries by asking the following questions: 1) Have overall levels of poverty increased, decreased or remained stable? 2) Has the incidence of poverty shifted from certain demographic groups to
VanDenBosch, Karel
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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