Results 141 to 150 of about 1,499,618 (334)
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Aid, the incentive regime, and poverty reduction [PDF]
Spurring growth in the developing world is one stated objective of foreign aid. Another, more commonly cited, objective is reducing poverty. Generally poverty reduction and growth go hand in hand, but could aid mitigate poverty without measurably ...
Burnside, Craig, Dollar, David
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
The Reality and Masquerade behind Bargaining over Welfare Pie Sizing, Delivery and Slicing. [PDF]
The present analysis addresses the apparently critical issue of circulation of wealth in society. Three actors play the game of welfare-related taxation.
Mullat, Joseph E.
core +1 more source
Pertumbuhan Ekonomi, Indeks Pembangunan Manusia, Utang Luar Negeri dan Kemiskinan (Kajian Teoritis di Indonesia) [PDF]
, 2015 This study was conducted with the intention of examining the causal relationship between the following variables: Human Development Index (HDI), foreign debt, poverty, and economic growth.
Suliswanto, M. S. (Muhammad) +1 more
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Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Determinants of Monetary Poverty in the European Union [PDF]
, 2012 The main objective of the study is to analyze the most important determinants of monetary poverty (at macro-level) in the Western EU countries taking into account the effects of regional spillovers.
Zelinsky, Tomas
core
Overcoming extreme poverty through the utilisation of Village Funds: A case study in Indonesia
Societal ImpactsThis study examines the effectiveness of the Village Fund in reducing extreme poverty in Indonesia through a mixed methods approach with a parallel convergent design.
Musa Hefer Smas +3 more
doaj +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source