Results 141 to 150 of about 1,584,796 (357)

Os professores do 1º ciclo de Águeda perante a pobreza infantil [PDF]

open access: yes, 2012
Mestrado em Ciências da EducaçãoA pobreza é um fenómeno complexo e multidimensional, como bem mostram os estudos nacionais e estrangeiros sobre este tema. Nos últimos tempos tem-se falado bastante sobre a pobreza em Portugal e no mundo.
Soares, Isabel Maria Vidal
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Reality and Masquerade behind Bargaining over Welfare Pie Sizing, Delivery and Slicing. [PDF]

open access: yes
The present analysis addresses the apparently critical issue of circulation of wealth in society. Three actors play the game of welfare-related taxation.
Mullat, Joseph E.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Development for all 2015-2020: strategy for strengthening disability-inclusive development in Australia’s aid program [PDF]

open access: yes
Disability-inclusive development is a priority for Australia’s international engagement. This strategy – Development for All 2015-2020: Strategy for strengthening disability-inclusive development in Australia’s aid program – responds to the agenda set ...
Department of Foreign Affairs and Trade
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy