Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Matthew Gandy and Alimuddin Zumla (eds), The return of the white plague: global poverty and the ‘new’ tuberculosis, London and New York, Verso, 2003, pp. vi, 330, £25.00 (hardback 1-85984-669-6). [PDF]
, 2005 John Welshman
openalex +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Does microcredit for the poverty-alleviated population have an income-increasing effect? Also on the "Raising the Low" effect. [PDF]
PLoS OneLiu Y, Fan L, Yan B.
europepmc +1 more source
Arab Republic of Egypt : Poverty Assessment Update, Volume 1. Main Report [PDF]
, 2007 openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Social mobility beliefs moderate links between SSS, attributions for wealth and poverty, and aggression. [PDF]
BMC PsycholZhu X, Gan J, Yang X.
europepmc +1 more source
POST‐TRANSITION POVERTY TRENDS BASED ON AN ALTERNATIVE DATA SOURCE1 [PDF]
, 2008 Servaas van der Berg +2 more
openalex +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source