Time poverty and teacher subjective well-being in an accelerated society: a three-wave longitudinal analysis of emotional exhaustion, psychological resilience, and gender. [PDF]
Wang K, Huang T, Lin X, Tan R.
europepmc +1 more source
Identifying sustainable pathways out of in-work poverty: Follow-up qualitative interviews report on the ‘Working Life in York’ survey : ESRC Knowledge Exchange Scheme ES/L002086/1 [PDF]
Rebecca Tunstall, Joanna K. Swaffield
openalex
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Determinants of health poverty vulnerability of rural households in Jiangxi Province, China: an analysis based on risk theory. [PDF]
Liu G, Wei Z, Wu C, Guo X, Hao M, Wan X.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Multidimensional poverty and health: an analysis of multidimensional poverty and its influencing factors among rural residents in Western China from a health ecology perspective. [PDF]
Li C, Hu Q, Ma X, He J, Xie Y, Qiao H.
europepmc +1 more source

