Results 251 to 260 of about 1,621,121 (389)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Persistent poverty, glycemic control and adverse COVID-19 outcomes: a retrospective study using real-world data. [PDF]

BMC Public Health
Tanaka S, Williams S, Zhang L, Yi N, Garvey WT, Cherrington AL, Howell CR.   +6 more
europepmc   +1 more source

1 Introduction: Unmet care needs and care poverty in international perspective [PDF]

Teppo Kröger, Nicola Brimblecombe, Ricardo Alexandre Cardoso Rodrigues, Kirstein Rummery   +3 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Social Determinants of Health: Analysis of the Effect of Socio-environmental Factors to Diseases, Injury-related DALYs, and Deaths based on WHO, ILO, and WB Data. [PDF]

Acta Med Philipp
Lu JL, Concepcion PL.
europepmc   +1 more source

Is Tower Hamlets Rich or Poor? Part 1: Poverty, income and employment

, 2013
Frederick Harry Pitts
openalex   +1 more source

Grounded theory approach in sermon analysis of sermons on poverty and directed at the poor as listeners¹

, 2011
HJC Pieterse
openalex   +2 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Child Poverty Trends by Race and Ethnicity in the US From 2022 to 2025.

JAMA Pediatr
Majeed H, Logie CH, Zuberi D.
europepmc   +1 more source

Association of Regional Agricultural Smoke Exposure With Sociodemographic Factors in Rural and Urban Communities. [PDF]

Geohealth
Slater KD, Young BN, Ford B, Adamo S, Fischer E, Gargulinski E, Henery GL, Pierce JR, Rosen Z, Sablan O, Soja A, Wiese LA, Williams CL, Magzamen S.   +13 more
europepmc   +1 more source