Results 251 to 260 of about 1,012,054 (376)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Lung cancer disparities in rural, persistent poverty counties: a secondary data analysis. [PDF]

BMC Public Health
Bernacchi V, Hirko K, Boakye EA, Tam S, Lucas T, Moss JL.   +5 more
europepmc   +1 more source

Jonathan Healey. The First Century of Welfare: Poverty and Poor Relief in Lancashire, 1620–1730. Woodbridge, UK: Boydell Press, 2014. xvi + 319 pp. ISBN: 978-1-84383-956-9, $29.95 (paper). [PDF]

, 2017
David Smith
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

The mediating role of physical activity on cognitive disparities in cancer survivors. [PDF]

JNCI Cancer Spectr
Allen JL, Rogers LQ, Martin MY, Amick BC.   +3 more
europepmc   +1 more source

Dynamics of rural transformation and poverty and inequality in Asia and the Pacific 1 [PDF]

, 2019
Katsushi S. Imai, Raghav Gaiha, Fabrizio Bresciani   +2 more
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Deeper Effects of fiscal multidimensional poverty reduction: household characteristics, financial lags and elite capture. [PDF]

PLoS One
Jiang W, Yang H, Liu C.
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Association Between Census Tract-Level Poverty and Non-White Race with Location of Coal Ash Disposal Pits in the United States. [PDF]

Int J Environ Res Public Health
Shingara EA, Weinberg C, McAlexander TP.
europepmc   +1 more source