Results 281 to 290 of about 2,178,916 (421)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Poverty (Number 1 Goal of the SDG) of Disabled People through Disability Studies and Ability Studies Lenses: A Scoping Review

Tsion Berie, Sean A. Kidd, Gregor Wolbring   +2 more
openalex   +1 more source

Conditions of Poverty, Parent–Child Interactions, and Toddlers’ Early Language Skills in Low-Income Families

Maternal and Child Health Journal, 2019
L. Justice, Hui Jiang, Kelly M. Purtell, Kammi K. Schmeer, K. Boone, Randi A. Bates, P. Salsberry   +6 more
semanticscholar   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Correction: Deeper effects of fiscal multidimensional poverty reduction: Household characteristics, financial lags and elite capture. [PDF]

PLoS One
Jiang W, Yang H, Liu C.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Manajemen Cash Waqf sebagai Instrumen Alternatif SDG-1 "Ending Poverty" di Indonesia

, 2022
Syaima Eugenia, Elvina Dian Paramita, Nisa Nurrahmah, Irfan Syauqi Beik   +3 more
openalex   +2 more sources

Rural multidimensional poverty and livelihood mix: A micro level study in Bihar, India. [PDF]

Heliyon
Onyeyirichi OA, Deepika MG.
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Leveraging social science research to combat poverty and inequality in the Middle East - a pathway to achieving SDGs 1 and 10

Chadi Azmeh, Hiba Darwich
openalex   +1 more source