Results 81 to 90 of about 258,784 (265)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Sengkarut kemiskinan masyarakat desa dalam novel Aib dan Nasib karya Minanto

Diglosia
This research was carried out with the aim of analyzing (1) the structure of “Aib dan Nasib” with heuristic reding, (2) the village and its chaos in poverty according to Robert Chambers' view, and (3) the reasons why the village community experiences a ...
Chintya Angesty, Eta Farmacelia Nurulhady, Sukarjo Waluyo   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Poverty and Social Transfers in Croatia [PDF]

Financial Theory and Practice, 2005
Various aspects of poverty in Croatia are still insufficiently well researched. Not only is there no knowledge about how long Croatian citizens remain poor, but there are also some disagreements about the actual number of the poor and the choice of the ...
Zoran Šuæur
doaj  

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

GOVERNANCE AND SUSTAINABLE DEVELOPMENT GOAL ONE (SDG1) “NO POVERTY” IN AFRICA

Management of Sustainable Development
This study investigates the impact of governance quality on the attainment of Sustainable Development Goal One (SDG1 – No Poverty) across 45 African countries between 2015 and 2021.
ABDULRAHMAN Idris Abdulganiyu, ABDULSALAM Abdulquddus Adewale   +1 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Mapping poverty and food security: A spatial correlation analysis in central java

World Development Sustainability
Poverty and food security are two closely interrelated global issues and are top priorities in the Sustainable Development Goals (SDGs) agenda, particularly SDG 1 (no poverty) and SDG 2 (no hunger).
Shanty Oktavilia, Firmansyah, Zainur Hidayah, Fauzul Adzim, Sucihatiningsih Dian Wisika Prajanti, Fafurida   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source