Results 91 to 100 of about 45,652,519 (319)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Discussion: “Lift and Pressure Fluctuations of a Cambered Airfoil Under Periodic Gusts and Applications in Turbomachinery” (Naumann, H., and Yeh, H., 1973, ASME J. Eng. Power, 95, pp. 1–10) [PDF]
J. H. Horlock
openalex +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cover Picture: Interplay of p‐Sulfonatocalix[4]arene and Crown Ethers En Route to Molecular Capsules and “Russian Dolls” (Chem. Eur. J. 10/2006) [PDF]
Scott J. Dalgarno +2 more
openalex +1 more source
SLIP: 10 years ago and 10 years from now [PDF]
Founded in 1999, the ACM SLIP Workshop is now in its 12th year. The 2010 SLIP Panel session will highlight perspectives from three individuals who have had great influence on the course of SLIP, and provide an opportunity for lively discussion by ...
Groeneveld, Patrick +2 more
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

