Results 161 to 170 of about 29,006,367 (387)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

RBCCV 100% digital BJCVS goes 100% digital

Brazilian Journal of Cardiovascular Surgery, 2010
Domingo M. Braile
doaj   +1 more source

Ginsenoside Rg1 inhibits angiogenesis in diabetic retinopathy through the miR‐100‐3p/FBXW7/c‐MYC molecular axis [PDF]

Liping Xue, Min Hu, Yadi Li, Qin Zhu, Guanglong Zhou, Xiaofan Zhang, Yuan Zhou, Jieying Zhang, Peng Ding   +8 more
openalex   +1 more source

أثر برنامج تدریبی بإستخدام تدریبات (القفزات المتتالیة) على القدرة العضلیة وزمن أداء سباحة 100 مترا زحف على البطن [PDF]

, 2022
عبــــــاس السیــــــد عبــــاس
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

100 Cities 100 Entrepreneurs

, 2014
https://digitalcommons.usu.edu/huntsman_news/1203/thumbnail ...
openaire   +1 more source

Estimation of 100-year-return-period temperatures in France in a non-stationary climate: Results from observations and IPCC scenarios

, 2007
Claudine Laurent, Sylvie Parey
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Professor Zerbini: 100 anos Professor Zerbini: 100 years

Brazilian Journal of Cardiovascular Surgery, 2012
Domingo M. Braile
doaj   +1 more source