Results 171 to 180 of about 29,006,367 (387)

MT 100

open access: yesDrugs in R & D, 2003
openaire   +2 more sources

100 years of glucagon and 100 more

open access: yesDiabetologia, 2023
N. J. Wewer Albrechtsen   +10 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

MicroRNA-100 (miR-100) [PDF]

open access: yesScience-Business eXchange, 2014
openaire   +1 more source

Investigation of the temperature in dense carbon near the solid-liquid phase transition between 100 GPa and 200 GPa with spectrally resolved X-ray scattering

open access: green, 2019
J. Helfrich   +20 more
openalex   +2 more sources

Valuing Health Conditions - Insights from Happiness Surveys across Countries and Cultures [PDF]

open access: yes
This paper assesses the effects of different health conditions on happiness. Based on a large data set for Latin America, the effects of different conditions are examined across age, gender, and income cohorts. Anxiety and pain have stronger effects than
Carol Graham   +2 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Les 100 médicaments essentiels. Une approche de médecine interne

open access: green, 2013
Mathew Thomas   +9 more
openalex   +2 more sources

Home - About - Disclaimer - Privacy