Results 21 to 30 of about 367,991 (224)
Journal of Lipid Research, 2018 Both miR-103 and miR-107 have been demonstrated to restrain cell proliferation and regulate lipid metabolism and inflammation. However, the effects of miR-103/107 on preadipocyte apoptosis remain unknown. In the present research, we have investigated how
Zhenzhen Zhang +4 more
semanticscholar +1 more source
Influenza A viruses circulating in dogs - a review of the scientific literature
Open Veterinary Journal, 2022 Influenza A viruses (IAV) cause persistent epidemics and occasional human pandemics, leading to considerable economic losses. The ecology and epidemiology of IAV are very complex and the emergence of novel zoonotic pathogens is one of the greatest ...
Nailya Klivleyeva +3 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2018 Adipose inflammation is an important cause for obesity-associated metabolic disorders, including insulin resistance and hypertension. Here we investigated that a circular RNA (circRNA), which we termed circARF3 (ADP-ribosylation factor 3), acts as an ...
Zhenzhen Zhang +5 more
semanticscholar +1 more source
MYC targeting by OMO-103 in solid tumors: a phase 1 trial
Nature MedicineAmong the ‘most wanted’ targets in cancer therapy is the oncogene MYC, which coordinates key transcriptional programs in tumor development and maintenance. It has, however, long been considered undruggable.
E. Garralda +20 more
semanticscholar +1 more source
Journal of Cellular and Molecular Medicine, 2019 Cardiac hypertrophy is a common pathological change frequently accompanied by chronic hypertension and myocardial infarction. Nevertheless, the pathophysiological mechanisms of cardiac hypertrophy have never been elucidated. Recent studies indicated that
Hanping Qi +9 more
semanticscholar +1 more source
Bioscience Reports, 2019 Objectives: The aim of the present study was to determine the effects of miRNA-103 on chondrocyte apoptosis and molecular mechanisms in osteoarthritis (OA) progression.
Fang Li +3 more
semanticscholar +1 more source
MicroRNA-103 contributes to osteoarthritis development by targeting Sox6.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019 Osteoarthritis is a degenerative joint disease, worldwide, and its underlying molecular mechanisms are still poorly understood. MicroRNAs are important regulators of diverse biological processes, including osteoarthritis.
Jian Chen, Xing Wu
semanticscholar +1 more source
Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells
Nanomaterials, 2018 Methylene blue (MB) is a widely used dye and photodynamic therapy (PDT) agent that can produce reactive oxygen species (ROS) after light exposure, triggering apoptosis.
Po-Ting Wu +5 more
doaj +1 more source
miR-103 promotes endothelial maladaptation by targeting lncWDR59
Nature Communications, 2018 Blood flow at arterial bifurcations and curvatures is naturally disturbed. Endothelial cells (ECs) fail to adapt to disturbed flow, which transcriptionally direct ECs toward a maladapted phenotype, characterized by chronic regeneration of injured ECs ...
L. Natarelli +8 more
semanticscholar +1 more source