Results 51 to 60 of about 74,398 (177)

Algorithms for Optimizing Vocabulary Acquisition in Language Learning

open access: yesProceedings of the International Conference on Applied Innovations in IT
This study addresses the critical role of dictionaries in language learning, emphasizing the need for effective navigation strategies to enhance vocabulary acquisition.
Tetiana Verhun   +5 more
doaj   +1 more source

Development and validation of a UPLC–MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
A simple and rapid UPLC–MS/MS method to simultaneously determine gemcitabine and its L-carnitine ester derivative (2'-deoxy-2', 2'-difluoro-N-((4-amino-4-oxobutanoyl) oxy)-4-(trimethyl amm-onio) butanoate-cytidine, JDR) in rat plasma was developed and ...
Gang Wang   +12 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

GIS as a tool to detect flat erosional surfaces in coastal areas: a case study in North Spain

open access: yesGeologica Acta, 2015
The delimitation of flat surfaces, such as marine or continental terraces, can be easily done if they are wellpreserved by using classic techniques such as fieldwork and photointerpretation.
M.J. DOMÍNGUEZ-CUESTA   +5 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Peculiarities of Implementing Multifractal Analysis of the Milled Surfaces Microrelief

open access: yesЖурнал інженерних наук
Manufacturing parts with a specific surface microrelief, which often determines their functional properties, is essential in various industry sectors.
Nataliia Balytska   +4 more
doaj   +1 more source

Lipid-albumin nanoassemblies co-loaded with borneol and paclitaxel for intracellular drug delivery to C6 glioma cells with P-gp inhibition and its tumor targeting

open access: yesAsian Journal of Pharmaceutical Sciences, 2015
Successful chemotherapy with paclitaxel (PTX) is impeded by multidrug resistance (MDR) in tumor cells. In this study, lipid-albumin nanoassemblies co-loaded with borneol and paclitaxel (BOR/PTX LANs) were prepared to circumvent MDR in C6 glioma cells ...
Bo Tang   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Presentación Letras 103

open access: yesLetras, 2023
Anny Gabriella Perales de Hernández
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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