Results 101 to 110 of about 1,883,513 (341)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Sustained Increased Consumption of Cigarettes, Alcohol, and Marijuana Among Manhattan Residents After September 11, 2001 [PDF]

, 2004
David Vlahov, Sandro Galea, Jennifer Ahern, Heidi S. Resnick, Dean G. Kilpatrick   +4 more
openalex   +3 more sources

Correction: Vannini, A.; Petraglia, A. Wood Distillate Mitigates Ozone-Induced Visible and Photosynthetic Plant Damage: Evidence from Ozone-Sensitive Tobacco (Nicotiana tabacum L.) BelW3. Horticulturae 2024, 10, 480

Horticulturae
In the original publication [...]
Andrea Vannini, Alessandro Petraglia
doaj   +1 more source

Flow network indices signal a directional change in ecosystems: Evidence from a small mountain lake (Lake Santo, northern Italy)

Ecological Indicators, 2022
Empirical evidence of the theoretically expected trends of ecosystem development is scarce so far. In this research, we used long-term empirical data about the plankton community of a small mountain lake (Lake Santo, northern Apennines, Italy) to ...
Marco Scotti, Cristina Bondavalli, Giampaolo Rossetti, Antonio Bodini   +3 more
doaj  

Food purchasing decisions and environmental ideology: an exploratory survey of UK shoppers [PDF]

, 2019
Environmentally and ethically conscious food purchasing has traction with British consumers. We examined how broad environmental worldviews related to shoppers’ ratings of the importance of various shopping criteria, including recognition of eco-labels ...
Christopher R. Jones, Erdogan, Francis Wong, Harrison, Jean M. Russell, Margo E. Barker, Schwartz, Streiner, Wellesley   +8 more
core   +2 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Assessing the climate impacts of oat straw as a raw material

Cleaner Materials, 2022
Straw is an interesting renewable feedstock for various high-value products, such as textile fibers. However, straw encompass to soils maintains a good soil structure, fertility, and carbon storage.
Lauri Leppäkoski, Ville Uusitalo, Susanna Horn, Jarkko Levänen, Heli Kasurinen, Anna Härri   +5 more
doaj  

Architectural and Management Strategies for the Design, Construction and Operation of Energy Efficient and Intelligent Primary Care Centers in Chile [PDF]

, 2019
Primary care centers are establishments with elevated social relevance and high operational energy consumption. In Chile, there more than 628 family healthcare centers (CESFAM) have been built in the last two decades and with plans for hundreds more in
Bobadilla, Ariel, Forcael, Eric, García Alvarado, Rodrigo, Nope Bernal, Alberto, Rubio Bellido, Carlos   +4 more
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source