Results 121 to 130 of about 1,438,481 (364)

The effects of nutrition on maternal mortality: Evidence from 19th-20th century Italy

open access: yesSSM: Population Health, 2020
The role of nutrition on maternal mortality has been long debated in the historical and scientific literature. Some scholars refute any role of nutrition and diet in the decline of maternal mortality, privileging other causes such as the diffusion of ...
Matteo Manfredini
doaj  

Sustainable Irrigation Management of Ornamental Cordyline Fruticosa “Red Edge” Plants with Saline Water [PDF]

open access: yes, 2019
The aim of this work was to analyze the influence of the salinity of the nutrient solution on the transpiration and growth of Cordyline fruticosa var. “Red Edge” plants. A specific irrigation management model was calibrated with the experimental data. An
Al-Hamdani   +18 more
core   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

City Blueprints: Baseline Assessments of Sustainable Water Management in 11 Cities of the Future [PDF]

open access: yesWater Resources Management, 2013
The necessity of Urban Water Cycle Services (UWCS) adapting to future stresses calls for changes that take sustainability into account. Megatrends (e.g. population growth, water scarcity, pollution and climate change) pose urgent water challenges in cities.
openaire   +5 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Family management and firm performance in family SMEs: the mediating roles of management control systems and technological innovation [PDF]

open access: yes, 2019
The aim of this research is to analyze the mediating role of the use of management control systems (MCS) and the achievement of technological innovation (TI) in the relationship between family management and firm performance in family small and medium ...
Anderson   +24 more
core   +3 more sources

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

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